Acquired Methemoglobinemia Observational Registry
Public ClinicalTrials.gov record NCT03542760. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Use of Methylene Blue in Acquired Methemoglobinemia: Prospective Observational Registry (metHb)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This prospective, observational registry aims to collect real-world data regarding the safety and efficacy of ProvayBlue® (methylene blue 0.5%) used according to normal standard of care for the treatment of acquired methemoglobinemia. Methylene blue has been used for decades as a rescue medication for the treatment of methemoglobinemia, a rare and potentially life-threatening condition in which elevated levels of methemoglobin impede the delivery of oxygen from blood to body tissues. However, consistent prospective data about the safety and efficacy of this medication are sparse, simply because of the rarity of the disorder. ProvayBlue® received accelerated FDA approval for treatment of acquired methemoglobinemia in 2016. This large, prospective, multi-center observational registry has been initiated to gain more information on the use of methylene blue in the treatment of acquired methemoglobinemia.
Study identification
- NCT ID
- NCT03542760
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 24 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2018 (Actual)
- Primary completion
- Jun 30, 2021 (Actual)
- Completion
- Aug 31, 2021 (Actual)
- Last update posted
- Apr 12, 2023
2018 – 2021
United States locations
- U.S. sites
- 32
- U.S. states
- 22
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cedars Sinai | Los Angeles | California | 90048 | — |
| UC Davis Health | Sacramento | California | 95817 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| Hartford Hospital | Hartford | Connecticut | 06106 | — |
| Palmetto General | Palm Beach Gardens | Florida | 33410 | — |
| Tampa General | Tampa | Florida | 33606 | — |
| IU Health | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas Health System | Kansas City | Kansas | 66160 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Partners Healthcare; Brigham and Women's | Boston | Massachusetts | 02115 | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| St John Medical Center | Detroit | Michigan | 48236 | — |
| HealthPartners Regions | Saint Paul | Minnesota | 55101 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| University of Nebraska | Omaha | Nebraska | 68198 | — |
| Holy Name Medical Center | Teaneck | New Jersey | 07666 | — |
| New York Methodist | New York | New York | 10032 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28207 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| University Hospitals | Cleveland | Ohio | 44106 | — |
| Mercy Health | Youngstown | Ohio | 44501 | — |
| Oregon Health & Sciences University | Portland | Oregon | 97239 | — |
| Einstein Medical Center | Philadelphia | Pennsylvania | 19141 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| University of Tennessee Health Science Center | Memphis | Tennessee | 38104 | — |
| UT Southwestern | Dallas | Texas | 75390 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Houston Methodist | Houston | Texas | 77030 | — |
| University of Washington | Seattle | Washington | 98195 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03542760, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2023 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03542760 live on ClinicalTrials.gov.