A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis
Public ClinicalTrials.gov record NCT03568318. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Subjects With Moderate to Severe Atopic Dermatitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to assess the efficacy and safety of upadacitinib combined with topical corticosteroids (TCS) for the treatment of adolescent and adult participants with moderate to severe atopic dermatitis (AD) who are candidates for systemic therapy.
Study identification
- NCT ID
- NCT03568318
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,533 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 9, 2018 (Actual)
- Primary completion
- Feb 16, 2021 (Actual)
- Completion
- Oct 23, 2030 (Estimated)
- Last update posted
- Dec 23, 2025
2018 – 2030
United States locations
- U.S. sites
- 59
- U.S. states
- 28
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Total Skin and Beauty Derm Ctr /ID# 200548 | Birmingham | Alabama | 35205 | — |
| Clinical Research Center AL /ID# 201865 | Birmingham | Alabama | 35209-6802 | — |
| ACCEL Research Sites /ID# 213364 | Birmingham | Alabama | 35218 | — |
| Advanced Dermatology and Skin Care Centre /ID# 213550 | Mobile | Alabama | 36605-3004 | — |
| Alliance Dermatology and MOHs Center, PC /ID#200540 | Phoenix | Arizona | 85032 | — |
| Arizona Research Center, Inc. /ID# 200546 | Phoenix | Arizona | 85053-4061 | — |
| Clear Dermatology & Aesthetics Center /ID# 201257 | Scottsdale | Arizona | 85255-4134 | — |
| University of Arizona /ID# 201059 | Tucson | Arizona | 85719 | — |
| Bakersfield Derma & Skin Cance /ID# 200892 | Bakersfield | California | 93309 | — |
| Mosaic Dermatology /ID# 200553 | Beverly Hills | California | 90211 | — |
| University of California Irvine /ID# 200902 | Irvine | California | 92697-1385 | — |
| Therapeutics Clinical Research /ID# 200593 | San Diego | California | 92123 | — |
| Stanford University /ID# 200597 | Stanford | California | 94305 | — |
| Duplicate_University of Colorado Anchutz Medical Campus /ID# 202822 | Aurora | Colorado | 80045-2517 | — |
| Colorado Center for Dermatology, PLLC /ID# 203626 | Centennial | Colorado | 80111-1724 | — |
| Duplicate_Western States Clinical Research, Inc. /ID# 201702 | Wheat Ridge | Colorado | 80033-2896 | — |
| Dermatology Physicians of Connecticut /ID# 201004 | Shelton | Connecticut | 06484-6211 | — |
| Clearlyderm Dermatology /ID# 207709 | Boca Raton | Florida | 33428 | — |
| Skin Care Research, LLC /ID# 200812 | Boca Raton | Florida | 33486-2269 | — |
| Clinical Research of West Florida, Inc /ID# 203643 | Clearwater | Florida | 33765 | — |
| Florida Academic Centers Research and Education /ID# 200544 | Coral Gables | Florida | 33134 | — |
| Tory P Sullivan, MD PA /ID# 201174 | North Miami Beach | Florida | 33162-4708 | — |
| Park Avenue Dermatology, PA /ID# 201012 | Orange Park | Florida | 32073 | — |
| Precision Clinical Research /ID# 208734 | Sunrise | Florida | 33351-7311 | — |
| Advanced Clinical Research at Treasure Valley Dermatology & Skin Cancer Center /ID# 203628 | Boise | Idaho | 83713 | — |
| Northwestern University Feinberg School of Medicine /ID# 201646 | Chicago | Illinois | 60611-2927 | — |
| Northshore University Health System Dermatology Clinical Trials Unit /ID# 200556 | Skokie | Illinois | 60077 | — |
| DuPage Medical Group /ID# 202065 | Wheaton | Illinois | 60189-3801 | — |
| Deaconess Clinic Downtown /ID# 201001 | Evansville | Indiana | 47713-1227 | — |
| Indiana University /ID# 200515 | Indianapolis | Indiana | 46202 | — |
| Epiphany Dermatology of Kansas LLC /ID# 203026 | Overland Park | Kansas | 66210 | — |
| ORA, Inc. /ID# 202824 | Andover | Massachusetts | 01810 | — |
| Tufts Medical Center /ID# 200570 | Boston | Massachusetts | 02111-1552 | — |
| Beth Israel Deaconess Medical Center /ID# 200545 | Boston | Massachusetts | 02215-5400 | — |
| Clin Res Inst of Michigan, LLC /ID# 208020 | Chesterfield | Michigan | 48047 | — |
| Michigan Center for Research Company /ID# 200560 | Clarkston | Michigan | 48346 | — |
| MediSearch Clinical Trials /ID# 201006 | Saint Joseph | Missouri | 64506 | — |
| Skin Specialists, PC /ID# 200573 | Omaha | Nebraska | 68144 | — |
| Dartmouth-Hitchcock Medical Center /ID# 200918 | Lebanon | New Hampshire | 03756 | — |
| Psoriasis Treatment Center of Central New Jersey /ID# 200714 | East Windsor | New Jersey | 08520 | — |
| Juva Skin and Laser Center /ID# 200997 | New York | New York | 10022-3204 | — |
| J. Schwartz, MD, PLLC /ID# 202122 | Troy | New York | 12180-2323 | — |
| Bexley Dermatology Research /ID# 200899 | Bexley | Ohio | 43209-2422 | — |
| The Ohio State University /ID# 200542 | Columbus | Ohio | 43210-1257 | — |
| Vital Prospects Clinical Research Institute, PC /ID# 200901 | Tulsa | Oklahoma | 74136-7049 | — |
| Oregon Dermatology and Research Center /ID# 200601 | Portland | Oregon | 97210 | — |
| University of Pittsburgh MC /ID# 206057 | Pittsburgh | Pennsylvania | 15260 | — |
| Rhode Island Hospital /ID# 200566 | Providence | Rhode Island | 02903 | — |
| AAPRI Clinical Research /ID# 221134 | Warwick | Rhode Island | 02886-2876 | — |
| Rivergate Dermatology & Skin Care Center /ID# 201698 | Goodlettsville | Tennessee | 37072-2301 | — |
| Stones River Dermatology /ID# 204962 | Murfreesboro | Tennessee | 37129-3194 | — |
| Arlington Research Center, Inc /ID# 200559 | Arlington | Texas | 76011 | — |
| Center for Clinical Studies /ID# 200582 | Houston | Texas | 77004 | — |
| Progressive Clinical Research /ID# 201582 | San Antonio | Texas | 78229 | — |
| Center for Clinical Studies - Webster TX /ID# 203186 | Webster | Texas | 77598 | — |
| Advanced Clinical Research - Woseth Dermatology /ID# 213745 | Salt Lake City | Utah | 84117-4209 | — |
| Eastern Virginia Med School /ID# 200994 | Norfolk | Virginia | 23507-1627 | — |
| Dermatology Associates of Seattle /ID# 200717 | Seattle | Washington | 98101 | — |
| University of Wisconsin - Madison /ID# 204933 | Madison | Wisconsin | 53715-1218 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 134 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03568318, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 23, 2025 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03568318 live on ClinicalTrials.gov.