Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder
Public ClinicalTrials.gov record NCT03572933. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized, Placebo-controlled Trial of Adjunctive Ganaxolone Treatment in Children and Young Adults With Cyclin-dependent Kinase-like 5 (CDKL5) Deficiency Disorder (CDD) Followed by Long-term Open-label Treatment
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A clinical study to evaluate the efficacy, safety, and tolerability of adjunctive ganaxolone therapy compared to placebo for the treatment of seizures in children and young adults with genetically confirmed CDKL5 gene mutation.
Study identification
- NCT ID
- NCT03572933
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 101 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 2 Years to 21 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2018 (Actual)
- Primary completion
- Jul 31, 2020 (Actual)
- Completion
- May 28, 2021 (Actual)
- Last update posted
- Apr 14, 2023
2018 – 2021
United States locations
- U.S. sites
- 17
- U.S. states
- 14
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Marinus Research Site | Phoenix | Arizona | 85016 | — |
| Marinus Research Site | Los Angeles | California | 90095-1742 | — |
| Marinus Research Site | Aurora | Colorado | 80045 | — |
| Marinus Research Site | Gulf Breeze | Florida | 32561 | — |
| Marinus Research Site | Orlando | Florida | 32819 | — |
| Marinus Research Site | Norcross | Georgia | 30093 | — |
| Marinus Research Site | Chicago | Illinois | 60612-3852 | — |
| Marinus Research Site | Iowa City | Iowa | 52242 | — |
| Marinus Research Site | Boston | Massachusetts | 02115 | — |
| Marinus Research Site | Rochester | Minnesota | 55905 | — |
| Marinus Research Site | St Louis | Missouri | 63130 | — |
| Marinus Research Site | Livingston | New Jersey | 07039 | — |
| Marinus Research Site | Cleveland | Ohio | 44195 | — |
| Marinus Research Site | Philadelphia | Pennsylvania | 19104-4318 | — |
| Marinus Research Site | Pittsburgh | Pennsylvania | 15224 | — |
| Marinus Research Site | Fort Worth | Texas | 76104 | — |
| Marinus Research Site | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03572933, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 14, 2023 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03572933 live on ClinicalTrials.gov.