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Active, not recruiting Phase 3 Interventional

A Study to Test Radium-223 With Docetaxel in Patients With Prostate Cancer

ClinicalTrials.gov ID: NCT03574571

Public ClinicalTrials.gov record NCT03574571. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 9:04 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase III Trial of Docetaxel vs. Docetaxel and Radium-223 for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to compare any good and bad effects of using radium-223 along with docetaxel chemotherapy treatment versus using docetaxel alone. Earlier studies helped show that the combination is safe, but the combination has not been proven to work better than either drug alone. The goal of this study is to find out if combining docetaxel and radium-223 is better than giving either drug by itself.

Study identification

NCT ID
NCT03574571
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Enrollment
732 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 19, 2018 (Actual)
Primary completion
Apr 1, 2027 (Estimated)
Completion
Apr 1, 2027 (Estimated)
Last update posted
May 14, 2026

2018 – 2027

United States locations

U.S. sites
40
U.S. states
23
U.S. cities
35
Facility City State ZIP Site status
Banner MD Anderson Cancer Center Gilbert Arizona 85234 —
Yale University- Yale Cancer Center New Haven Connecticut 06510 —
Helen Graham Cancer Center (Christiana Care) Newark Delaware 19713 —
Boca Raton Regional Hospital Boca Raton Florida 33486 —
Mount Sinai Medical Center (Miami) Miami Florida 33140 —
Rush University Medical Center Chicago Illinois 606012 —
Indiana University Indianapolis Indiana 46202 —
Ochsner Cancer Institute New Orleans Louisiana 70121 —
University of Maryland Medical Center Baltimore Maryland 21201 —
University of Massachusetts Worcester Massachusetts 01655 —
University of Michigan Cancer Center Ann Arbor Michigan 48109 —
University of Minnesota Minneapolis Minnesota 55455 —
Nebraska Cancer Specialists Omaha Nebraska 68114 —
XCancer Omaha / Urology Cancer Center Omaha Nebraska 68130 —
Comprehensive Cancer Centers of Nevada Las Vegas Nevada 89128 —
Memorial Sloan Kettering Basking Ridge Basking Ridge New Jersey 07920 —
MD Anderson Cancer Center at Cooper Camden New Jersey 08103 —
Memorial Sloan Kettering Monmouth Middletown New Jersey 07748 —
Memorial Sloan Kettering Bergen Montvale New Jersey 07645 —
New Jersey Urology Saddle Brook New Jersey 07663 —
New Mexico Oncology and Hematology Albuquerque New Mexico 87109 —
University of Buffalo Buffalo New York 14203 —
Roswell Park Cancer Institute Buffalo New York 14263-0001 —
Memorial Sloan Kettering Commack Commack New York 11725 —
Memorial Sloan Kettering Westchester Harrison New York 10604 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
New York Presbyterian Hospital-Weill Medical College of Cornell University New York New York 10065 —
Bronx VA Hospital New York New York 10468 —
University of Rochester Medical Center Rochester New York 14642 —
Memorial Sloan Kettering Nassau Uniondale New York 11553 —
University of North Carolina Chapel Hill North Carolina 27514 —
Atrium Health/ Levine Cancer Institute Monroe North Carolina 28112 —
University of Cincinnati Medical Center Cincinnati Ohio 45219 —
Dayton Physicians Network Kettering Ohio 45409 —
University of Oklahoma Oklahoma City Oklahoma 73104 —
MidLantic Urology Bala-Cynwyd Pennsylvania 19004 —
Medical University of South Carolina Charleston South Carolina 29425 —
Houston Methodist Research Institute Houston Texas 77030 —
Millennium Physicians Houston Texas 77090 —
University of Washington Seattle Washington 98109 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03574571, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 14, 2026 · Synced Oct 24, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03574571 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →