A Study to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects With High-risk, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas
Public ClinicalTrials.gov record NCT03575351. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Global Randomized Multicenter Phase 3 Trial of JCAR017 Compared to Standard of Care in Adult Subjects With High-risk, Second-line, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas (TRANSFORM).
Study identification
- NCT ID
- NCT03575351
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Celgene
- Industry
- Enrollment
- 184 participants
Conditions and interventions
Conditions
Interventions
- JCAR017 Genetic
- Standard of Care Drug
Genetic · Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 22, 2018
- Primary completion
- Oct 22, 2023
- Completion
- Oct 22, 2023
- Last update posted
- Aug 2, 2025
2018 – 2023
United States locations
- U.S. sites
- 28
- U.S. states
- 19
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 129 | Scottsdale | Arizona | 85258 | — |
| Local Institution - 116 | Scottsdale | Arizona | 85259 | — |
| Local Institution - 115 | San Francisco | California | 94143 | — |
| Local Institution - 106 | Aurora | Colorado | 80045 | — |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | — |
| Local Institution - 126 | Tampa | Florida | 33612 | — |
| Local Institution - 108 | Atlanta | Georgia | 30322 | — |
| Local Institution - 107 | Atlanta | Georgia | 30342 | — |
| Local Institution - 122 | Chicago | Illinois | 60611 | — |
| Loyola University Medical Center Cardinal Bernardin Cancer Center | Maywood | Illinois | 60153 | — |
| Local Institution - 102 | Boston | Massachusetts | 02114 | — |
| Local Institution - 104 | Boston | Massachusetts | 02215 | — |
| Local Institution - 120 | Ann Arbor | Michigan | 48109 | — |
| Local Institution - 119 | Detroit | Michigan | 48201 | — |
| Local Institution - 112 | Minneapolis | Minnesota | 55455 | — |
| Local Institution - 103 | Rochester | Minnesota | 55905-0001 | — |
| Local Institution - 100 | Omaha | Nebraska | 68198 | — |
| Local Institution - 121 | Hackensack | New Jersey | 07601 | — |
| Local Institution - 111 | Buffalo | New York | 14263 | — |
| Local Institution - 117 | New York | New York | 10065 | — |
| Local Institution - 125 | Charlotte | North Carolina | 28204 | — |
| Local Institution - 127 | Oklahoma City | Oklahoma | 73104 | — |
| Local Institution - 101 | Portland | Oregon | 97239 | — |
| Local Institution - 123 | Pittsburgh | Pennsylvania | 15232 | — |
| Local Institution - 109 | Dallas | Texas | 75246 | — |
| Local Institution - 124 | Houston | Texas | 77030 | — |
| Local Institution - 114 | Richmond | Virginia | 23298 | — |
| Local Institution - 110 | Seattle | Washington | 98109-4417 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03575351, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 2, 2025 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03575351 live on ClinicalTrials.gov.