ClinicalTrials.gov record
Recruiting Phase 2 Interventional

Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders

ClinicalTrials.gov ID: NCT03579875

Public ClinicalTrials.gov record NCT03579875. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 12:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

MT2017-17:T Cell Receptor Alpha/Beta T Cell Depleted Hematopoietic Cell Transplantation in Patients With Inherited Bone Marrow Failure (BMF) Disorders

Study identification

NCT ID
NCT03579875
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Enrollment
48 participants

Conditions and interventions

Interventions

  • Alemtuzumab Drug
  • Busulfan Drug
  • Cyclophosphamide (CY) (Plan 1) Drug
  • Cyclophosphamide (CY) (Plan 2) Drug
  • Donor mobilized PBSC infusion Device
  • Fludarabine (FLU) Drug
  • G-CSF Drug
  • Melphalan Drug
  • Methylprednisolone (MP) Drug
  • Rituximab Drug
  • Total Body Irradiation (TBI) (Plan 1) Drug

Drug · Device

Eligibility (public fields only)

Age range
Up to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 12, 2018
Primary completion
Dec 31, 2026
Completion
Jan 4, 2029
Last update posted
Jan 29, 2026

2018 – 2029

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Masonic Cancer Center at University of Minnesota Minneapolis Minnesota 55455 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03579875, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 29, 2026 · Synced May 8, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03579875 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →