Efficacy and Safety of CUSA-081 in the Restoration of Central Venous Access Device (CVAD) Functionality
Public ClinicalTrials.gov record NCT03594175. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Active and Placebo-Controlled Study on the Use of CUSA-081 for Dysfunctional Central Venous Access Devices (CVADs)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To evaluate the efficacy and safety of CUSA-081 (diluted reteplase) in the restoration of central venous access device (CVAD) functionality in participants 18 years and older.
Study identification
- NCT ID
- NCT03594175
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 462 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 12, 2020 (Actual)
- Primary completion
- Jun 8, 2023 (Actual)
- Completion
- Jul 10, 2023 (Actual)
- Last update posted
- Aug 23, 2024
2020 – 2023
United States locations
- U.S. sites
- 35
- U.S. states
- 23
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Chiesi Investigational Site | Little Rock | Arkansas | 72205 | — |
| Chiesi Investigational Site | Redlands | California | 92373 | — |
| Chiesi Investigational Site | Stockton | California | 95204 | — |
| Chiesi Investigational Site | Norwich | Connecticut | 06360 | — |
| Chiesi Investigational Site | Newark | Delaware | 19718 | — |
| Chiesi Investigational Site | Jacksonville | Florida | 32209 | — |
| Chiesi Investigational Site | Miami | Florida | 33155-3009 | — |
| Chiesi Investigational Site | Plantation | Florida | 33322 | — |
| Chiesi Investigational Site | Weeki Wachee | Florida | 34607 | — |
| Chiesi Investigational Site | Weston | Florida | 33331 | — |
| Chiesi Investigational Site | Atlanta | Georgia | 30322 | — |
| Chiesi Investigational Site | Honolulu | Hawaii | 96814 | — |
| Chiesi Investigational Site | Quincy | Illinois | 62301 | — |
| Chiesi Investigational Site | New Albany | Indiana | 47150 | — |
| Einspahr | Topeka | Kansas | 66606 | — |
| Chiesi Investigational Site | Lewiston | Maine | 04240 | — |
| Chiesi Investigational Site | Hannibal | Missouri | 63401 | — |
| Chiesi Investigational Site | Kalispell | Montana | 59901-3158 | — |
| Chiesi Investigational Site | Omaha | Nebraska | 68131 | — |
| Chiesi Investigational Site | Howell Township | New Jersey | 07731 | — |
| Chiesi Investigational Site | New Brunswick | New Jersey | 08901 | — |
| Chiesi Investigational Site | Durham | North Carolina | 27710 | — |
| Chiesi Investigational Site | Winston-Salem | North Carolina | 27103 | — |
| Chiesi Investigational Site | Toledo | Ohio | 43608 | — |
| Chiesi Investigational Site | Toledo | Ohio | 43614 | — |
| Chiesi Investigational Site | Oklahoma City | Oklahoma | 73104 | — |
| Chiesi Investigational Site | Bend | Oregon | 97701 | — |
| Chiesi Investigational Site | Portland | Oregon | 97210 | — |
| Chiesi Investigational Site | Bethlehem | Pennsylvania | 18015 | — |
| Chiesi Investigational Site | Charleston | South Carolina | 29414 | — |
| Chiesi Investigational Site | Spartanburg | South Carolina | 29303 | — |
| Chiesi Investigational Site | Franklin | Tennessee | 37067 | — |
| Chiesi Investigational Site | Knoxville | Tennessee | 37920 | — |
| Chiesi Investigational Site | Fredericksburg | Virginia | 22401 | — |
| Chiesi Investigational Site | Lynchburg | Virginia | 24501 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03594175, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 23, 2024 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03594175 live on ClinicalTrials.gov.