ClinicalTrials.gov record
Terminated Phase 3 Interventional Results available

Efficacy and Safety of CUSA-081 in the Restoration of Central Venous Access Device (CVAD) Functionality

ClinicalTrials.gov ID: NCT03594175

Public ClinicalTrials.gov record NCT03594175. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 17, 2026, 6:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Randomized, Double-Blind, Active and Placebo-Controlled Study on the Use of CUSA-081 for Dysfunctional Central Venous Access Devices (CVADs)

Study identification

NCT ID
NCT03594175
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Chiesi Farmaceutici S.p.A.
Industry
Enrollment
462 participants

Conditions and interventions

Interventions

  • Alteplase Drug
  • CUSA-081 Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 11, 2020
Primary completion
Jun 7, 2023
Completion
Jul 9, 2023
Last update posted
Aug 22, 2024

2020 – 2023

United States locations

U.S. sites
35
U.S. states
23
U.S. cities
34
Facility City State ZIP Site status
Chiesi Investigational Site Little Rock Arkansas 72205
Chiesi Investigational Site Redlands California 92373
Chiesi Investigational Site Stockton California 95204
Chiesi Investigational Site Norwich Connecticut 06360
Chiesi Investigational Site Newark Delaware 19718
Chiesi Investigational Site Jacksonville Florida 32209
Chiesi Investigational Site Miami Florida 33155-3009
Chiesi Investigational Site Plantation Florida 33322
Chiesi Investigational Site Weeki Wachee Florida 34607
Chiesi Investigational Site Weston Florida 33331
Chiesi Investigational Site Atlanta Georgia 30322
Chiesi Investigational Site Honolulu Hawaii 96814
Chiesi Investigational Site Quincy Illinois 62301
Chiesi Investigational Site New Albany Indiana 47150
Einspahr Topeka Kansas 66606
Chiesi Investigational Site Lewiston Maine 04240
Chiesi Investigational Site Hannibal Missouri 63401
Chiesi Investigational Site Kalispell Montana 59901-3158
Chiesi Investigational Site Omaha Nebraska 68131
Chiesi Investigational Site Howell Township New Jersey 07731
Chiesi Investigational Site New Brunswick New Jersey 08901
Chiesi Investigational Site Durham North Carolina 27710
Chiesi Investigational Site Winston-Salem North Carolina 27103
Chiesi Investigational Site Toledo Ohio 43608
Chiesi Investigational Site Toledo Ohio 43614
Chiesi Investigational Site Oklahoma City Oklahoma 73104
Chiesi Investigational Site Bend Oregon 97701
Chiesi Investigational Site Portland Oregon 97210
Chiesi Investigational Site Bethlehem Pennsylvania 18015
Chiesi Investigational Site Charleston South Carolina 29414
Chiesi Investigational Site Spartanburg South Carolina 29303
Chiesi Investigational Site Franklin Tennessee 37067
Chiesi Investigational Site Knoxville Tennessee 37920
Chiesi Investigational Site Fredericksburg Virginia 22401
Chiesi Investigational Site Lynchburg Virginia 24501

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03594175, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 22, 2024 · Synced May 17, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03594175 live on ClinicalTrials.gov.

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