ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

ClinicalTrials.gov ID: NCT03603808

Public ClinicalTrials.gov record NCT03603808. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 7:27 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Evaluation of VGX-3100, a Synthetic DNA Immunotherapy Targeting Human Papillomavirus 16 and 18 E6 and E7 Proteins, for Anal High-Grade Squamous Intraepithelial Lesions (HSIL) in HIV-Positive Individuals

Study identification

NCT ID
NCT03603808
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AIDS Malignancy Consortium
Network
Enrollment
44 participants

Conditions and interventions

Interventions

  • Electroporation Device
  • HPV DNA Plasmids Therapeutic Vaccine VGX-3100 Biological
  • Laboratory Biomarker Analysis Other

Device · Biological · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 20, 2018
Primary completion
Dec 30, 2024
Completion
Jun 16, 2025
Last update posted
May 7, 2026

2018 – 2025

United States locations

U.S. sites
7
U.S. states
6
U.S. cities
7
Facility City State ZIP Site status
University of California, San Francisco San Francisco California 94143
Grady Health System Atlanta Georgia 30303
Anal Dysplasia Clinic MidWest Chicago Illinois 60614
Boston Medical Center Boston Massachusetts 02118
Laser Surgery Care New York New York 10011
Montefiore Medical Center The Bronx New York 10461
Wake Forest Baptist health Sciences Winston-Salem North Carolina 27157

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03603808, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 7, 2026 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03603808 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →