ClinicalTrials.gov record
SI-6603 (Condoliase) Study for Lumbar Disc Herniation (Discovery 6603 Study)
ClinicalTrials.gov ID: NCT03607838
Public ClinicalTrials.gov record NCT03607838. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-blind, Sham-controlled, Comparative Study of SI-6603 in Subjects With Lumbar Disc Herniation (Phase 3)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is to evaluate the effectiveness of a single-dose intervertebral disc injection of SI-6603 in subjects with lumbar disc herniation (LDH)
Study identification
- NCT ID
- NCT03607838
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 352 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 30 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 7, 2018 (Actual)
- Primary completion
- Aug 3, 2022 (Actual)
- Completion
- Mar 21, 2023 (Actual)
- Last update posted
- Jul 24, 2025
2018 – 2023
United States locations
- U.S. sites
- 67
- U.S. states
- 27
- U.S. cities
- 63
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Delta Clinical Research | Mobile | Alabama | 36609 | — |
| Pain Medicine Associates, Inc. | Fountain Valley | California | 92708 | — |
| University of California San Diego - Center for Pain Medicine | La Jolla | California | 92037 | — |
| The Helm Center for Pain Management | Laguna Woods | California | 92637 | — |
| The Anand Spine Group | Los Angeles | California | 90048 | — |
| VA Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| Samaritan Center for Medical Research | Los Gatos | California | 95032 | — |
| UC Davis Spine Center | Sacramento | California | 95816 | — |
| Source Healthcare | Santa Monica | California | 90403 | — |
| Boulder Neurosurgical Associates | Boulder | Colorado | 80303 | — |
| DBPS Research, LLC | Greenwood Village | Colorado | 80111 | — |
| International Spine, Pain, and Performance Center | Washington D.C. | District of Columbia | 20006 | — |
| Florida Spine Institute | Clearwater | Florida | 33765 | — |
| Spine and Orthopedic Center | Deerfield Beach | Florida | 33441 | — |
| Deland Clinical research Unit | DeLand | Florida | 32720 | — |
| Science Connections, LLC | Doral | Florida | 33166 | — |
| Coastal Clinical Research | Fernandina Beach | Florida | 32034 | — |
| Holy Cross Medical Group | Fort Lauderdale | Florida | 33334 | — |
| Coastal Clinical Research | Jacksonville | Florida | 32224 | — |
| Genoma Research Group, Inc. | Miami | Florida | 33155 | — |
| Science Connections, LLC (Kendall) | Miami | Florida | 33175 | — |
| AMPM Research Clinic | Miami Gardens | Florida | 33169 | — |
| Pain Relief Centers | St. Petersburg | Florida | 33709 | — |
| Pain Relief Centers | Sun City Center | Florida | 33573 | — |
| Tampa Pain Relief Center | Tampa | Florida | 33603 | — |
| Florida Pain Relief Group, PLLC | Tampa | Florida | 33614 | — |
| Premier Medical Associates | The Villages | Florida | 32159 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Augusta University - Medical College of Georgia | Augusta | Georgia | 30912 | — |
| Georgia Institute for Clinical Research, LLC | Marietta | Georgia | 30060 | — |
| Injury Care Research | Boise | Idaho | 83713 | — |
| Millennium Pain Center | Bloomington | Illinois | 61704 | — |
| Chicago Anesthesia Pain Specialists | Chicago | Illinois | 60657 | — |
| Indiana Spine Group | Carmel | Indiana | 46032 | — |
| Neuroscience Research Center LLC | Overland Park | Kansas | 66210 | — |
| OtriMed Clinical Research | Edgewood | Kentucky | 41017 | — |
| Clinical Trials of Southwest Louisiana, LLC | Lake Charles | Louisiana | 70601 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| St. Louis Pain Consultants | Chesterfield | Missouri | 63017 | — |
| Comprehensive and Interventional Pain Management LLP | Henderson | Nevada | 89052 | — |
| Innovative Pain Care Center | Las Vegas | Nevada | 89106 | — |
| Interventional Spine Medicine | Barrington | New Hampshire | 03825 | — |
| New Jersey Regenerative Institute | Cedar Knolls | New Jersey | 07927 | — |
| New York - Presbyterian Queens | Flushing | New York | 11355 | — |
| Drug Trials America | Hartsdale | New York | 10530 | — |
| Ainsworth Institute Of Pain Management | New York | New York | 10022 | — |
| University of Rochester- Neuromedicine Pain Management Center | Rochester | New York | 14618 | — |
| The Center for Clinical Research | Winston-Salem | North Carolina | 27103 | — |
| Clinical Inquest Center Ltd | Beavercreek | Ohio | 45431 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| META Medical Research Institute | Dayton | Ohio | 45432 | — |
| Medical Research International | Oklahoma City | Oklahoma | 73109 | — |
| Oklahoma City Clinical Research Center | Oklahoma City | Oklahoma | 73159 | — |
| Main Line Spine | King of Prussia | Pennsylvania | 19406 | — |
| Clinical Trials of South Carolina | Charleston | South Carolina | 29406 | — |
| SC Pain & Spine Specialists | Murrells Inlet | South Carolina | 29576 | — |
| Ascension Spine and Scoliosis Center | Austin | Texas | 78731 | — |
| HRMD Research | Dallas | Texas | 75240 | — |
| Advanced Medical Trials | Georgetown | Texas | 78628 | — |
| Interventional Pain Specialists | Pasadena | Texas | 77505 | — |
| ARH Research, LLC. | The Woodlands | Texas | 77382 | — |
| JBR Clinical Research | Salt Lake City | Utah | 84107 | — |
| University of Virginia Orthopaedic Spine Center | Charlottesville | Virginia | 22903 | — |
| Virginia iSpine Physicians, P.C. | Richmond | Virginia | 23235 | — |
| Gershon Pain Specialists | Virginia Beach | Virginia | 23454 | — |
| Swedish Pain Management | Seattle | Washington | 98122 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03607838, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 24, 2025 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03607838 live on ClinicalTrials.gov.