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Active, not recruiting Phase 2 Interventional

Treatment Free Remission After Combination Therapy With Ruxolitinib Plus Tyrosine Kinase Inhibitors

ClinicalTrials.gov ID: NCT03610971

Public ClinicalTrials.gov record NCT03610971. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 6:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Treatment Free Remission After Combination Therapy With Ruxolitinib Plus Tyrosine Kinase Inhibitors in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine if adding Ruxolitinib to a Tyrone Kinase Inhibitor (TKI), prior to a second attempt at stopping a TKI will lead to prolonged treatment free remission (TFR).

Study identification

NCT ID
NCT03610971
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Enrollment
24 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 19, 2019 (Actual)
Primary completion
Sep 25, 2025 (Actual)
Completion
Oct 2026 (Estimated)
Last update posted
Apr 2, 2026

2019 – 2026

United States locations

U.S. sites
8
U.S. states
7
U.S. cities
8
Facility City State ZIP Site status
H. Lee Moffitt Cancer Center and Research Institute Tampa Florida 33612 —
Emory -Winship Cancer Institute Atlanta Georgia 30322 —
Memorial Sloan Kettering - Bergen Montvale New Jersey 07645 —
Roswell Park Comprehensive Cancer Center Buffalo New York 14263 —
David H. Koch Center for Cancer Care at Memorial Sloan Kettering New York New York 10021 —
Duke University Hospital Durham North Carolina 27710 —
Oregon Health & Science University Portland Oregon 97239 —
Froedtert Hospital & the Medical College of Wisconsin Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03610971, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 2, 2026 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03610971 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →