The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT03631225. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Vectra InVolved Informed Decision Outcome Study (VIVID): A Prospective Randomized Controlled Trial Evaluating the Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of treating patients diagnosed with rheumatoid arthritis (RA) is to achieve remission or low disease activity and thereby prevent joint damage, loss of physical function, and disability. Optimal management requires regular assessment of disease activity, with treatment changes made as needed for optimal efficacy. Vectra is a blood serum test that looks at 12 biomarkers and produces a score on a scale of 1 to 100. The Vectra score has been shown to be the strongest predictor of risk for progression of disease. There is opportunity to gain more information about the utility of Vectra in a real-world clinical setting. This study will, therefore, evaluate the utility of Vectra for guiding treatment decisions and improving RA-related outcomes in comparison with usual care, which will not include Vectra testing. This study will enable a direct evaluation of the clinical benefit associated with using Vectra to guide treatment decisions in patients with RA.
Study identification
- NCT ID
- NCT03631225
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 1,500 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 25, 2019 (Actual)
- Primary completion
- Jul 1, 2026 (Actual)
- Completion
- Jul 15, 2026 (Actual)
- Last update posted
- Jul 21, 2026
2019 – 2026
United States locations
- U.S. sites
- 30
- U.S. states
- 14
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Bio Solutions Clinical Research | La Mesa | California | 91942 | — |
| Brigid Freyne, MD | Murrieta | California | 92563 | — |
| J. Lee MD Medical Corp | Orange | California | 92868 | — |
| Delaware Arthritis | Lewes | Delaware | 19958 | — |
| AARDS Research, Inc. | Aventura | Florida | 33180 | — |
| Robert W. Levin, MD, PA | Clearwater | Florida | 33765 | — |
| Artemisa Analytics | Miami | Florida | 33133 | — |
| Rheumatology Associates of Central Florida, P.A. | Orlando | Florida | 32806 | — |
| Clin-Med Research & Development, LLC | South Miami | Florida | 33141 | — |
| Accurate Clinical Research | Lake Charles | Louisiana | 70605 | — |
| Arthritis and Diabetes Clinic, Inc. | Monroe | Louisiana | 71203 | — |
| North Mississippi Medical Center | Tupelo | Mississippi | 38801 | — |
| Clinvest Research, LLC. | Springfield | Missouri | 65810 | — |
| Rheumatology Associates of Long Island | Smithtown | New York | 11787 | — |
| Paramount Medical Research & Consulting, LLC | Middleburg Heights | Ohio | 44130 | — |
| Southern Ohio Rheumatology Inc. | Wheelersburg | Ohio | 45694 | — |
| East Penn Rheumatology Associates, P.C. | Bethlehem | Pennsylvania | 18015 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Advanced Rheumatology & Arthritis Research Center, PC | Wexford | Pennsylvania | 15090 | — |
| PA Regional Center for Arthritis and Osteoporosis Research | Wyomissing | Pennsylvania | 19610 | — |
| Carolina Health Specialists | Myrtle Beach | South Carolina | 29572 | — |
| Accurate Clinical Research | Baytown | Texas | 77521 | — |
| Pioneer Research Solutions, Inc | Cypress | Texas | 77429 | — |
| Accurate Clinical Research | Houston | Texas | 77089 | — |
| CardioVoyage | Sherman | Texas | 75090 | — |
| Center for Arthritis and Rheumatic Diseases, P.C. | Chesapeake | Virginia | 23320 | — |
| Arthritis and Osteoporosis Center of Northern Virginia | Manassas | Virginia | 20109 | — |
| Center for Arthritis and Rheumatic Diseases., P.C. | Suffolk | Virginia | 23435 | — |
| Arthritis Northwest, PLLC | Spokane | Washington | 99204 | — |
| Aurora Rheumatology and Immunotherapy Center | Franklin | Wisconsin | 53132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03631225, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 21, 2026 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03631225 live on ClinicalTrials.gov.