Gene Therapy for APOE4 Homozygote of Alzheimer's Disease
Public ClinicalTrials.gov record NCT03634007. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 52-Week, Multicenter, Phase 1/2 Open-label Study to Evaluate the Safety of LX1001 in Participants With APOE4 Homozygote Alzheimer's Disease
Study identification
- NCT ID
- NCT03634007
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Lexeo Therapeutics
- Industry
- Enrollment
- 15 participants
Conditions and interventions
Conditions
Interventions
- LX1001 Biological
Biological
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 5, 2019
- Primary completion
- Nov 6, 2024
- Completion
- Nov 6, 2024
- Last update posted
- Oct 19, 2025
2019 – 2024
United States locations
- U.S. sites
- 4
- U.S. states
- 3
- U.S. cities
- 4
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| K2 Medical Research | Maitland | Florida | 32751 | — |
| PPD- Orlando Research Unit | Orlando | Florida | 32806 | — |
| Weill Cornell Medicine | New York | New York | 10021 | — |
| Duke University | Durham | North Carolina | 27708 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03634007, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 19, 2025 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03634007 live on ClinicalTrials.gov.