Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors
Public ClinicalTrials.gov record NCT03645928. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter Study of Autologous Tumor Infiltrating Lymphocytes (LN 144/LN-145/LN-145-S1) in Patients With Solid Tumors
Study identification
- NCT ID
- NCT03645928
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Iovance Biotherapeutics, Inc.
- Industry
- Enrollment
- 245 participants
Conditions and interventions
Conditions
Interventions
- Carboplatin Drug
- Cisplatin Drug
- Ipilimumab Drug
- LN-145 Biological
- LN-145-S1 Biological
- Lifileucel Biological
- Nab-Paclitaxel Drug
- Nivolumab Drug
- Nivolumab-relatlimab Drug
- Paclitaxel Drug
- Pembrolizumab Drug
- Pemetrexed Drug
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 6, 2019
- Primary completion
- Aug 8, 2029
- Completion
- Aug 8, 2029
- Last update posted
- Jun 18, 2025
2019 – 2029
United States locations
- U.S. sites
- 24
- U.S. states
- 16
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California, San Diego | La Jolla | California | 92093 | Terminated |
| University of Southern California | Los Angeles | California | 90007 | Active, not recruiting |
| University of California, Los Angeles | Los Angeles | California | 90095 | Active, not recruiting |
| University of Colorado | Denver | Colorado | 80045 | Active, not recruiting |
| Yale University | New Haven | Connecticut | 06520 | Active, not recruiting |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | Active, not recruiting |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | Withdrawn |
| Orlando Health Cancer Institute | Orlando | Florida | 32610 | Recruiting |
| Moffitt Cancer Center | Tampa | Florida | 33612 | Active, not recruiting |
| University of Louisville | Louisville | Kentucky | 40292 | Recruiting |
| University of Maryland | Baltimore | Maryland | 21201 | Active, not recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | Active, not recruiting |
| Henry Ford Health System | Detroit | Michigan | 48202 | Active, not recruiting |
| MD Anderson at Cooper | Camden | New Jersey | 08103 | Recruiting |
| Morristown Medical Center | Morristown | New Jersey | 07960 | Recruiting |
| Columbia University | New York | New York | 10027 | Withdrawn |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Active, not recruiting |
| University of Cincinnati | Cincinnati | Ohio | 45219 | Terminated |
| Ohio State University | Columbus | Ohio | 43201 | Recruiting |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | Withdrawn |
| Huntsman Cancer Hospital | Salt Lake City | Utah | 84112 | Withdrawn |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Terminated |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03645928, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 18, 2025 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03645928 live on ClinicalTrials.gov.