ClinicalTrials.gov record
A Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Moderately to Severely Active Ulcerative Colitis
ClinicalTrials.gov ID: NCT03653026
Public ClinicalTrials.gov record NCT03653026. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 18, 2026, 1:02 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study to Evaluate the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects With Moderately to Severely Active Ulcerative Colitis
Study identification
- NCT ID
- NCT03653026
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 522 participants
Conditions and interventions
Conditions
Not listed
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 16 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 5, 2018
- Primary completion
- Jan 13, 2021
- Completion
- Jan 13, 2021
- Last update posted
- Mar 1, 2022
2018 – 2021
United States locations
- U.S. sites
- 114
- U.S. states
- 33
- U.S. cities
- 93
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| East View Medical Research, LLC /ID# 216933 | Mobile | Alabama | 36606 | — |
| CB Flock Research Corporation /ID# 206094 | Mobile | Alabama | 36608 | — |
| Arizona Arthritis & Rheumatology Research, PLLC /ID# 211030 | Sun City | Arizona | 85306 | — |
| Digestive Disease Consultants, A Division of Arizona Digestive Health, P.C /ID# 211887 | Tempe | Arizona | 85284-2604 | — |
| University of Arizona /ID# 208856 | Tucson | Arizona | 85724 | — |
| Citrus Valley Gastroenterology /ID# 205627 | Covina | California | 91722-3797 | — |
| Care Access Research /ID# 217003 | Huntington Beach | California | 92648-5994 | — |
| Moore UC San Diego Cancer Center /ID# 204919 | La Jolla | California | 92093 | — |
| United Medical Doctors /ID# 207867 | Los Alamitos | California | 90720-3309 | — |
| TLC Clinical Research Inc /ID# 216831 | Los Angeles | California | 90048 | — |
| Gastrointestinal Biosciences Clinical Trials, LLC /ID# 205314 | Los Angeles | California | 90067-2001 | — |
| Facey Medical Foundation /ID# 205301 | Mission Hills | California | 91345 | — |
| United Medical Doctors - Murrieta /ID# 205313 | Murrieta | California | 92563 | — |
| InSite Digestive Health Care - Oxnard /ID# 205628 | Oxnard | California | 93030 | — |
| Inland Empire Clinical Trials, LLC /ID# 216164 | Rialto | California | 92377 | — |
| San Diego Clinical Trials /ID# 212122 | San Diego | California | 92120 | — |
| Medical Assoc Research Grp /ID# 205626 | San Diego | California | 92123 | — |
| Delta Waves, Inc. /ID# 206170 | Colorado Springs | Colorado | 80918 | — |
| Western States Clinical Res /ID# 206091 | Wheat Ridge | Colorado | 80033-2896 | — |
| Western Connecticut Medical Group /ID# 208290 | Danbury | Connecticut | 06810-6000 | — |
| Gastroenterology Center of CT /ID# 208291 | Hamden | Connecticut | 06518 | — |
| Gastro Florida /ID# 206174 | Clearwater | Florida | 33756 | — |
| Universal Axon Clinical Research /ID# 213462 | Doral | Florida | 33166 | — |
| Palmetto Research, LLC /ID# 208293 | Hialeah | Florida | 33016 | — |
| Nature Coast Clinical Research - Inverness /ID# 206087 | Inverness | Florida | 34452-4717 | — |
| Encore Borland-Groover Clinical Research /Id# 208128 | Jacksonville | Florida | 32256 | — |
| Cfagi Llc /Id# 207995 | Maitland | Florida | 32751-6108 | — |
| University of Miami /ID# 215445 | Miami | Florida | 33136 | — |
| Coral Research Clinic /ID# 208292 | Miami | Florida | 33186-4643 | — |
| Advanced Research Institute, Inc /ID# 206077 | New Port Richey | Florida | 34653 | — |
| Endoscopic Research, Inc. /ID# 207360 | Orlando | Florida | 32803 | — |
| Omega Research Consultants /ID# 206066 | Orlando | Florida | 32810 | — |
| Clinical Research Trials of Florida, Inc. /ID# 206068 | Tampa | Florida | 33607 | — |
| University of South Florida /ID# 214495 | Tampa | Florida | 33612 | — |
| AdventHealth Tampa /ID# 207363 | Tampa | Florida | 33613-4680 | — |
| Gastroenterology Associates of Central Georgia, LLC /ID# 216940 | Macon | Georgia | 31201 | — |
| Infinite Clinical Trials /ID# 215343 | Riverdale | Georgia | 30274 | — |
| Atlanta Gastroenterology Spec /ID# 206173 | Suwanee | Georgia | 30024 | — |
| Next Innovative Clinical Research - Chicago /ID# 217324 | Chicago | Illinois | 60605-2168 | — |
| The University of Chicago Medical Center /ID# 206172 | Chicago | Illinois | 60637-1443 | — |
| Carle Foundation Hospital /ID# 207397 | Effingham | Illinois | 62401 | — |
| MediSphere Medical Research Center /ID# 206073 | Evansville | Indiana | 47714-8011 | — |
| Indianapolis Gastroenterology /ID# 206381 | Indianapolis | Indiana | 46237 | — |
| University of Iowa Hospitals and Clinics /ID# 206167 | Iowa City | Iowa | 52242 | — |
| Cotton-O'Neil Clinical Res Ctr /ID# 206175 | Topeka | Kansas | 66606 | — |
| Tri-State Gastroenterology /ID# 206124 | Crestview Hills | Kentucky | 41017 | — |
| Houma Digestive Health Special /ID# 206176 | Houma | Louisiana | 70360 | — |
| Louisana Research Center, LLC /ID# 206064 | Shreveport | Louisiana | 71105-6800 | — |
| Gastro Center of Maryland /ID# 206883 | Columbia | Maryland | 21045 | — |
| University of Michigan Health Systems /ID# 206918 | Ann Arbor | Michigan | 48109 | — |
| Huron Gastroenterology Assoc /ID# 205109 | Ann Arbor | Michigan | 48197 | — |
| Clin Res Inst of Michigan, LLC /ID# 207078 | Chesterfield | Michigan | 48047 | — |
| Revival Research Institute, LLC /ID# 207282 | Southfield | Michigan | 48034-1659 | — |
| Center for Digestive Health /ID# 207080 | Troy | Michigan | 48098-6363 | — |
| Mayo Clinic /ID# 205645 | Rochester | Minnesota | 55905-0001 | — |
| University of Mississippi Medical Center /ID# 213116 | Jackson | Mississippi | 39216-4500 | — |
| Southern Therapy and Advanced Research (STAR) LLC /ID# 206069 | Jackson | Mississippi | 39216 | — |
| Las Vegas Medical Research /ID# 206814 | Las Vegas | Nevada | 89113 | — |
| AGA Clinical Research Associates, LLC /ID# 206880 | Egg Harbor | New Jersey | 08234 | — |
| Atlantic Digestive Health Inst /ID# 208748 | Morristown | New Jersey | 07960 | — |
| Rutgers Robert Wood Johnson /ID# 207382 | New Brunswick | New Jersey | 08901 | — |
| University of New Mexico Department of Internal Medicine /ID# 214397 | Albuquerque | New Mexico | 87131-0001 | — |
| NY Scientific /ID# 206080 | Brooklyn | New York | 11235 | — |
| NYU Langone Long Island Clinical Research Associates /ID# 206079 | Lake Success | New York | 11042 | — |
| DiGiovanna Institute for Medical Education & Research /ID# 206885 | North Massapequa | New York | 11758 | — |
| Premier Medical Group - GI Division /ID# 206097 | Poughkeepsie | New York | 12601 | — |
| Gastro Group of Rochester /ID# 206881 | Rochester | New York | 14618-5703 | — |
| Richmond University Medical Center /ID# 213185 | Staten Island | New York | 10310-1664 | — |
| Advantage Clinical Trials /ID# 206082 | The Bronx | New York | 10468 | — |
| Digestive Health Partners, P.A /ID# 206842 | Asheville | North Carolina | 28801 | — |
| Atrium Health Carolinas Medical Center /ID# 206085 | Charlotte | North Carolina | 28203 | — |
| Charlotte Gastroenterology and Hepatology, PLLC /ID# 206138 | Charlotte | North Carolina | 28207 | — |
| Wake Forest Baptist Medical Center /ID# 206067 | Winston-Salem | North Carolina | 27157-0001 | — |
| Duplicate_Plains Clinical Research Center, LLC /ID# 205111 | Fargo | North Dakota | 58104 | — |
| University of Cincinnati /ID# 205633 | Cincinnati | Ohio | 45267-0585 | — |
| The Ohio State University /ID# 205637 | Columbus | Ohio | 43210 | — |
| Optimed Research, Ltd. /ID# 205638 | Columbus | Ohio | 43235 | — |
| Hometown Urgent Care and Resea /ID# 205630 | Dayton | Ohio | 45424 | — |
| Dayton Gastroenterology, Inc. /ID# 205639 | Englewood | Ohio | 45415 | — |
| Great Lakes Gastroenterology Research LLC /ID# 205631 | Mentor | Ohio | 44060-6211 | — |
| Hightower Clinical /ID# 216336 | Oklahoma City | Oklahoma | 73102 | — |
| Digestive Disease Specialists /ID# 206076 | Oklahoma City | Oklahoma | 73112 | — |
| Options Health Research, LLC /ID# 206707 | Tulsa | Oklahoma | 74104 | — |
| Healthcare Research Consultant /ID# 206706 | Tulsa | Oklahoma | 74135 | — |
| Guthrie Medical Group, PC /ID# 206078 | Sayre | Pennsylvania | 18840 | — |
| Pharmacorp Clinical Trials /ID# 206074 | Charleston | South Carolina | 29412 | — |
| Gastroenterology Associates, P.A. of Greenville /ID# 206098 | Greenville | South Carolina | 29615-3593 | — |
| Gastro One /ID# 206178 | Germantown | Tennessee | 38138 | — |
| East Tennessee Research Institute /ID# 206169 | Johnson City | Tennessee | 37604 | — |
| Quality Medical Research /ID# 206088 | Nashville | Tennessee | 37211 | — |
| Vanderbilt University Medical Center /ID# 210405 | Nashville | Tennessee | 37232-0011 | — |
| TX Clinical Research Institute /ID# 206718 | Arlington | Texas | 76012 | — |
| Inquest Clinical Research /ID# 206132 | Baytown | Texas | 77521 | — |
| Texas Digestive Disease Consultants /ID# 209805 | Cedar Park | Texas | 78613-5028 | — |
| Texas Digestive Disease Consultants /ID# 209948 | Cedar Park | Texas | 78613-5028 | — |
| Baylor Scott & White Center for Inflammatory Bowel Diseases /ID# 207484 | Dallas | Texas | 75246 | — |
| DHAT Research Institute /ID# 206716 | Garland | Texas | 75044-2208 | — |
| Vilo Research Group Inc /ID# 212625 | Houston | Texas | 77017-2337 | — |
| Baylor College of Medicine - Baylor Medical Center /ID# 206717 | Houston | Texas | 77030-3411 | — |
| Centex Studies, Inc. - Houston /ID# 206168 | Houston | Texas | 77058 | — |
| GI Specialists of Houston /ID# 206090 | Houston | Texas | 77070-4347 | — |
| Caprock Gastro Research /ID# 215115 | Lubbock | Texas | 79424-3017 | — |
| Clinical Associates in Research Therapeutics of America, LLC /ID# 206710 | San Antonio | Texas | 78212 | — |
| Southern Star Research Institute, LLC /ID# 205379 | San Antonio | Texas | 78229-5390 | — |
| Baylor Scott & White Center for Diagnostic Medicine /ID# 206096 | Temple | Texas | 76508 | — |
| Duplicate_Tyler Research Institue /ID# 206075 | Tyler | Texas | 75701 | — |
| Gastro Health & Nutrition - Victoria /ID# 205378 | Victoria | Texas | 77904 | — |
| Advanced Research Institute /ID# 206133 | Ogden | Utah | 84403 | — |
| Ctr for Gastrointestinal Healt /ID# 208475 | Franklin | Virginia | 23851 | — |
| Washington Gastroenterology Associates /ID# 206177 | Bellevue | Washington | 98004 | — |
| Virginia Mason - Seattle Orthapedics /ID# 206070 | Seattle | Washington | 98101 | — |
| The Vancouver Clinic, INC. PS /ID# 204973 | Vancouver | Washington | 98664 | — |
| Wisconsin Center for Advanced Research, a division of GI Associates, LLC /ID# 206917 | Milwaukee | Wisconsin | 53215 | — |
| Froedtert Memorial Lutheran Hospital /ID# 206945 | Milwaukee | Wisconsin | 53226-3522 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 71 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03653026, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 1, 2022 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03653026 live on ClinicalTrials.gov.