A Study to Evaluate the Efficacy and Safety of Gefapixant (MK-7264) in Women With Endometriosis-Related Pain (MK-7264-034)
Public ClinicalTrials.gov record NCT03654326. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Proof of Concept, Randomized, Double-Blind, Placebo-Controlled Clinical Trial, to Evaluate the Efficacy and Safety of MK-7264 in Women With Moderate to Severe Endometriosis-Related Pain
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy, safety, and tolerability of gefapixant (MK-7264) in premenopausal female participants with moderate to severe endometriosis-related pain. The primary hypothesis: gefapixant is superior to placebo in reducing the average daily pelvic pain score (cyclic and non-cyclic, combined) during Treatment Cycle 2.
Study identification
- NCT ID
- NCT03654326
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 187 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 49 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 11, 2018 (Actual)
- Primary completion
- Jun 30, 2020 (Actual)
- Completion
- Jun 30, 2020 (Actual)
- Last update posted
- Nov 4, 2024
2018 – 2020
United States locations
- U.S. sites
- 30
- U.S. states
- 14
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Medical Care ( Site 0750) | Birmingham | Alabama | 35218 | — |
| Synexus US Phoenix Southeast ( Site 0729) | Chandler | Arizona | 85224 | — |
| Synexus ( Site 0734) | Scottsdale | Arizona | 85251 | — |
| Lynn Institute of the Ozarks ( Site 0720) | Little Rock | Arkansas | 72205 | — |
| California Center for Clinical Research ( Site 0741) | Arcadia | California | 91007 | — |
| Artemis Institute for Clinical Research ( Site 0716) | San Diego | California | 92103 | — |
| Alta California Medical Group ( Site 0721) | Simi Valley | California | 93065 | — |
| Thameside OBGYN Center ( Site 0747) | Groton | Connecticut | 06340 | — |
| WHUSA Fine and Gillette ( Site 0751) | Hamden | Connecticut | 06518 | — |
| Florida Fertility Institute ( Site 0737) | Clearwater | Florida | 33759 | — |
| Advanced Pharma Research ( Site 0719) | Cutler Bay | Florida | 33189 | — |
| Doral Medical Research, LLC ( Site 0706) | Doral | Florida | 33166 | — |
| KO Clinical Research, LLC ( Site 0723) | Fort Lauderdale | Florida | 33316 | — |
| Well Pharma Medical Research, Corp. ( Site 0703) | Miami | Florida | 33143 | — |
| L&C Professional Medical Research Institute ( Site 0709) | Miami | Florida | 33144 | — |
| New Horizon Research Center ( Site 0717) | Miami | Florida | 33465 | — |
| Inpatient Research Clinic, LLC ( Site 0725) | Miami Lakes | Florida | 33014 | — |
| QPS Miami Research Associates ( Site 0735) | South Miami | Florida | 33143 | — |
| Lenus Research & Medical Group Llc ( Site 0702) | Sweetwater | Florida | 33172 | — |
| Southern Clinical Research Associates ( Site 0701) | Metairie | Louisiana | 70001 | — |
| Tufts Medical Center ( Site 0742) | Boston | Massachusetts | 02111 | — |
| Carolina Women's Research and Wellness Center ( Site 0715) | Durham | North Carolina | 27713 | — |
| Palmetto Clinical Research ( Site 0707) | Summerville | South Carolina | 29485 | — |
| Chattanooga Medical Research ( Site 0743) | Chattanooga | Tennessee | 37404 | — |
| Women Partners in Health ( Site 0745) | Austin | Texas | 78705 | — |
| Corpus Christi Clinic ( Site 0744) | Corpus Christi | Texas | 78412 | — |
| HD Research Corp ( Site 0738) | Houston | Texas | 77024 | — |
| PI-Coor Clinical Research, LLC ( Site 0710) | Reston | Virginia | 20190 | — |
| Clinical Research Partners, LLC. ( Site 0704) | Richmond | Virginia | 23225 | — |
| Seattle Women's: Health, Research, Gynecology ( Site 0714) | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 48 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03654326, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 4, 2024 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03654326 live on ClinicalTrials.gov.