ClinicalTrials.gov record
Active, not recruiting Phase 1 Interventional

IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer

ClinicalTrials.gov ID: NCT03655002

Public ClinicalTrials.gov record NCT03655002. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 4, 2026, 5:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b Trial of the IRX-2 Regimen and Nivolumab in Patients With Advanced Hepatocellular Cancer (HCC)

Study identification

NCT ID
NCT03655002
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
City of Hope Medical Center
Other
Enrollment
8 participants

Conditions and interventions

Interventions

  • Cyclophosphamide Drug
  • Cytokine-based Biologic Agent IRX-2 Biological
  • Nivolumab Biological

Drug · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 20, 2019
Primary completion
Mar 1, 2027
Completion
Mar 1, 2027
Last update posted
Apr 19, 2026

2019 – 2027

United States locations

U.S. sites
3
U.S. states
3
U.S. cities
3
Facility City State ZIP Site status
HonorHealth Research Institute Scottsdale Arizona 85258
City of Hope Medical Center Duarte California 91010
Texas Oncology at Baylor Charles A Sammons Cancer Center Dallas Texas 75246

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03655002, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 19, 2026 · Synced May 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03655002 live on ClinicalTrials.gov.

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