An Open-label, 8-week Safety, Efficacy, and Assessment of Cooling Methods for Administration of CNTX-4975-05 for Knee OA
Public ClinicalTrials.gov record NCT03661996. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label, 8-Week Study to Compare the Comfort and Ease of Use of Five Different Treatment Regimens for CNTX-4975-05 Intra-articular Injection in Subjects With Chronic, Moderate-to-Severe Osteoarthritis Knee Pain
Study identification
- NCT ID
- NCT03661996
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Centrexion Therapeutics
- Industry
- Enrollment
- 854 participants
Conditions and interventions
Conditions
Interventions
- Breg Ice Water Pump Device
- CNTX-4975-05 Drug
- ElastoGel Device
- Lidocaine without epinephrine Drug
Device · Drug
Eligibility (public fields only)
- Age range
- 40 Years to 95 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 17, 2018
- Primary completion
- Oct 21, 2019
- Completion
- Oct 21, 2019
- Last update posted
- Mar 8, 2022
2018 – 2019
United States locations
- U.S. sites
- 28
- U.S. states
- 13
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Orthopaedic Center-Research | Birmingham | Alabama | 35209 | — |
| Holland Center for Family Health | Peoria | Arizona | 85381 | — |
| Noble Clinical Research | Tucson | Arizona | 85704 | — |
| Med Center Medical Clinic | Carmichael | California | 95608 | — |
| Core Healthcare Group | Cerritos | California | 90703 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| Conquest Clinical Research | Maitland | Florida | 32751 | — |
| F&T Medical Research, Inc. | Miami | Florida | 33184 | — |
| M&M Medical Center, Inc. | Miami | Florida | 33185 | — |
| Charter Research | Mt. Dora | Florida | 32757 | — |
| Premier MED Family & Sports Medicine | Ocoee | Florida | 34761 | — |
| Ascension Research | Pinellas Park | Florida | 33781 | — |
| M&M Clinical Trials Sunrise | Sunrise | Florida | 33351 | — |
| Georgia Institute for Clinical Research, LLC | Marietta | Georgia | 30060 | — |
| Atlanta Orthopaedic Institute, LLC | Stockbridge | Georgia | 30281 | — |
| Healthcare Research Network II, LLC | Flossmoor | Illinois | 60422 | — |
| Affinity Health | Oak Brook | Illinois | 60523 | — |
| MediSphere Medical Research Center, LLC | Evansville | Indiana | 47714 | — |
| Tandem Clinical Research | Marrero | Louisiana | 70072 | — |
| DelRicht Research | New Orleans | Louisiana | 70115 | — |
| Healthcare Research Network | Hazelwood | Missouri | 63042 | — |
| Center for Pharmaceutical Research, LLC | Kansas City | Missouri | 64114 | — |
| Office of Robert P. Kaplan, DO | Las Vegas | Nevada | 89119 | — |
| Hassman Research Institute | Berlin | New Jersey | 08009 | — |
| First Surgical Hospital | Bellaire | Texas | 77401 | — |
| Metroplex Clinical Research Center | Dallas | Texas | 75231 | — |
| Hermann Drive Surgical Hospital | Houston | Texas | 77004 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03661996, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 8, 2022 · Synced May 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03661996 live on ClinicalTrials.gov.