ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

Phase 3 Study of OTO-104 in Subjects With Unilateral Meniere's Disease

ClinicalTrials.gov ID: NCT03664674

Public ClinicalTrials.gov record NCT03664674. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 6:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Prospective, Randomized, Double Blind, Placebo-controlled, Multicenter, Phase 3 Efficacy and Safety Study of OTO-104 Given as a Single Intratympanic Injection in Subjects With Unilateral Meniere's Disease

Study identification

NCT ID
NCT03664674
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Otonomy, Inc.
Industry
Enrollment
148 participants

Conditions and interventions

Interventions

  • OTO-104 Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 26, 2018
Primary completion
Dec 21, 2020
Completion
Dec 21, 2020
Last update posted
Dec 6, 2022

2018 – 2020

United States locations

U.S. sites
17
U.S. states
13
U.S. cities
17
Facility City State ZIP Site status
Central California Clinical Research Fresno California 93720
University of Colorado School of Medicine Aurora Colorado 80045
Colorado ENT & Allergy Colorado Springs Colorado 80909
Yale University School of Medicine New Haven Connecticut 06510
Ear, Nose and Throat Associates of South Florida Boynton Beach Florida 33426
Ear Research Foundation Sarasota Florida 34239
Tandem Clinical Research Marrero Louisiana 70072
Michigan Ear Institute Farmington Hills Michigan 48334
Saint Louis University St Louis Missouri 63110
Dent Neurologic Institute Amherst New York 14226
New York Eye and Ear Infirmary of Mount Sinai New York New York 10003
Charlotte Eye Ear Nose & Throat Associates, P.A. Matthews North Carolina 28105
Piedmont Ear, Nose, and Throat Associates, PA Winston-Salem North Carolina 27103
Medical University of South Carolina, Department of Otolaryngology Charleston South Carolina 29425
Vanderbilt University Medical Center Nashville Tennessee 37232
Intermountain Ear, Nose & Throat Specialists Draper Utah 84020
West Virginia University School of Medicine Morgantown West Virginia 26506

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 48 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03664674, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 6, 2022 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03664674 live on ClinicalTrials.gov.

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