ClinicalTrials.gov record
Terminated Phase 2 Interventional Results available

A Study to Assess the Effects of RO6889450 (Ralmitaront) in Participants With Schizophrenia or Schizoaffective Disorder and Negative Symptoms

ClinicalTrials.gov ID: NCT03669640

Public ClinicalTrials.gov record NCT03669640. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 1:31 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Effects of RO6889450 (Ralmitaront) in Patients With Schizophrenia or Schizoaffective Disorder and Negative Symptoms

Study identification

NCT ID
NCT03669640
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
131 participants

Conditions and interventions

Interventions

  • Placebo Drug
  • RO6889450 Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 3, 2018
Primary completion
Mar 11, 2023
Completion
Mar 11, 2023
Last update posted
Aug 11, 2024

2018 – 2023

United States locations

U.S. sites
28
U.S. states
10
U.S. cities
26
Facility City State ZIP Site status
CITrials, Inc. Bellflower California 90706
Collaborative Neuroscience Network, Inc. Garden Grove California 92845
California Clinical Trials Glendale California 91206
Synergy San Diego Lemon Grove California 91945
Catalina Research Institute LLC - MRA Montclair California 91763
CITrials, Inc. Riverside California 92506
California Neuropsychopharmacology Clinical Research Institute, LLC San Diego California 92102
Stanford University School of Medicine Stanford California 94305
Collaborative Neuroscience Network Inc. Torrance California 90502
Yale School of Medicine - CT Mental Health Center (CMHC) - Schizophrenia Research Clinic New Haven Connecticut 06519
Innovative Clinical Research, Inc. Lauderhill Florida 33319
Lifestream Behavioral Center Leesburg Florida 34748
Advanced Research Institute of Miami Miami Florida 33135
Health Synergy Clinical Research Okeechobee Florida 34972
Emory University Atlanta Georgia 30329
Northwestern University Chicago Illinois 60611-2908
CBH Health Gaithersburg Maryland 20877
Precise Research Centers Flowood Mississippi 39232
Psych Care Consultants Research St Louis Missouri 63128
Millennium Psychiatric Associates, LLC St Louis Missouri 63132
Manhattan Psychiatric Center; Psychopharmacology Research Unit New York New York 10035
JPS Health Network Fort Worth Texas 76104
Pillar Clinical Research LLC Garland Texas 75042
Baylor College of Medicine Houston Texas 77030
University Hills Clinical Research Irving Texas 75062
The Solace Center Missouri City Texas 77459
Psychiatry & Behavioral Center Richmond Texas 77406
@ Health Texas Richmond Texas 77407

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03669640, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 11, 2024 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03669640 live on ClinicalTrials.gov.

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