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Terminated Phase 2 Interventional Results available

A Study to Assess the Effects of RO6889450 (Ralmitaront) in Participants With Schizophrenia or Schizoaffective Disorder and Negative Symptoms

ClinicalTrials.gov ID: NCT03669640

Public ClinicalTrials.gov record NCT03669640. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 1:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Effects of RO6889450 (Ralmitaront) in Patients With Schizophrenia or Schizoaffective Disorder and Negative Symptoms

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study investigates the effects of RO6889450 on the negative symptoms associated with schizophrenia and schizoaffective disorder.

Study identification

NCT ID
NCT03669640
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
131 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 4, 2018 (Actual)
Primary completion
Mar 12, 2023 (Actual)
Completion
Mar 12, 2023 (Actual)
Last update posted
Aug 12, 2024

2018 – 2023

United States locations

U.S. sites
28
U.S. states
10
U.S. cities
26
Facility City State ZIP Site status
CITrials, Inc. Bellflower California 90706 —
Collaborative Neuroscience Network, Inc. Garden Grove California 92845 —
California Clinical Trials Glendale California 91206 —
Synergy San Diego Lemon Grove California 91945 —
Catalina Research Institute LLC - MRA Montclair California 91763 —
CITrials, Inc. Riverside California 92506 —
California Neuropsychopharmacology Clinical Research Institute, LLC San Diego California 92102 —
Stanford University School of Medicine Stanford California 94305 —
Collaborative Neuroscience Network Inc. Torrance California 90502 —
Yale School of Medicine - CT Mental Health Center (CMHC) - Schizophrenia Research Clinic New Haven Connecticut 06519 —
Innovative Clinical Research, Inc. Lauderhill Florida 33319 —
Lifestream Behavioral Center Leesburg Florida 34748 —
Advanced Research Institute of Miami Miami Florida 33135 —
Health Synergy Clinical Research Okeechobee Florida 34972 —
Emory University Atlanta Georgia 30329 —
Northwestern University Chicago Illinois 60611-2908 —
CBH Health Gaithersburg Maryland 20877 —
Precise Research Centers Flowood Mississippi 39232 —
Psych Care Consultants Research St Louis Missouri 63128 —
Millennium Psychiatric Associates, LLC St Louis Missouri 63132 —
Manhattan Psychiatric Center; Psychopharmacology Research Unit New York New York 10035 —
JPS Health Network Fort Worth Texas 76104 —
Pillar Clinical Research LLC Garland Texas 75042 —
Baylor College of Medicine Houston Texas 77030 —
University Hills Clinical Research Irving Texas 75062 —
The Solace Center Missouri City Texas 77459 —
Psychiatry & Behavioral Center Richmond Texas 77406 —
@ Health Texas Richmond Texas 77407 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03669640, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 12, 2024 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03669640 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →