ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease

ClinicalTrials.gov ID: NCT03671889

Public ClinicalTrials.gov record NCT03671889. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 3:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Assessment of Safety and Efficacy of ExAblate Blood-Brain Barrier Disruption for the Treatment of Patients With Probable Alzheimer's Disease

Study identification

NCT ID: NCT03671889
Recruitment status: Recruiting
Study type: Interventional
Phase: Not applicable
Lead sponsor: InSightec; Industry
Enrollment: 50 participants

Conditions and interventions

Conditions

Alzheimer Disease

Interventions

Blood Brain Barrier (BBB) Disruption Device

Device

Eligibility (public fields only)

Age range: 50 Years to 85 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Sep 27, 2018
Primary completion: Dec 31, 2027
Completion: Dec 31, 2029
Last update posted: Jan 8, 2026

2018 – 2030

United States locations

U.S. sites: 10
U.S. states: 5
U.S. cities: 10

Facility	City	State	ZIP	Site status
Delray Medical Center & Florida Atlantic University	Delray Beach	Florida	33484	Recruiting
Broward Health Medical Center & The University of Florida	Fort Lauderdale	Florida	33316	Recruiting
University of Florida Health Shands	Gainesville	Florida	32608	Recruiting
Baptist Health South Florida & Florida International University	Miami	Florida	33176	Recruiting
Advent Health	Orlando	Florida	34747	Recruiting
Tampa General Hospital	Tampa	Florida	33612	Recruiting
Weill Cornell Medicine	New York	New York	10065	Active, not recruiting
The Ohio State University -Wexner Medical Center	Columbus	Ohio	43210	Active, not recruiting
University of Texas Southwestern Medical Center	Dallas	Texas	75390	Active, not recruiting
West Virginia University Rockefeller Neuroscience Center	Morgantown	West Virginia	26506	Active, not recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT03671889, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jan 8, 2026 · Synced May 8, 2026

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The complete protocol, eligibility criteria, and contact information for NCT03671889 live on ClinicalTrials.gov.

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