A Study Comparing Risankizumab to Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Have a History of Inadequate Response to or Intolerance to at Least One Disease Modifying Anti-Rheumatic Drug (DMARD) Therapy
Public ClinicalTrials.gov record NCT03675308. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Study Comparing Risankizumab to Placebo in Subjects With Active Psoriatic Arthritis (PsA) Who Have a History of Inadequate Response to or Intolerance to at Least One Disease Modifying Anti-Rheumatic Drug (DMARD) Therapy (KEEPsAKE 1)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the safety and efficacy of risankizumab versus placebo in participants with moderately to severely active psoriatic arthritis (PsA).
Study identification
- NCT ID
- NCT03675308
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 964 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 25, 2019 (Actual)
- Primary completion
- Oct 8, 2020 (Actual)
- Completion
- Sep 28, 2026 (Estimated)
- Last update posted
- Aug 5, 2025
2019 – 2026
United States locations
- U.S. sites
- 59
- U.S. states
- 24
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group /ID# 167955 | Anniston | Alabama | 36207 | — |
| Sun Valley Arthritis Center Ltd. /ID# 200270 | Peoria | Arizona | 85381 | — |
| AZ Arthritis and Rheumotology Research, PLLC /ID# 209873 | Phoenix | Arizona | 85032-9306 | — |
| Arizona Arthritis & Rheumatology Research, PLLC /ID# 209875 | Tucson | Arizona | 85704 | — |
| Southern Arizona VA Health Care System /ID# 209247 | Tucson | Arizona | 85723 | — |
| Arthritis and Rheumatism Associates /ID# 209882 | Jonesboro | Arkansas | 72401-6251 | — |
| Valerius Medical Group & Research Center /ID# 207428 | Los Alamitos | California | 90720-5402 | — |
| Rheumatology Center of San Diego /ID# 201642 | San Diego | California | 92128-2549 | — |
| Inland Rheum Clin Trials Inc. /ID# 201641 | Upland | California | 91786 | — |
| Medvin Clinical Research /ID# 211127 | Whittier | California | 90606 | — |
| New England Research Associates, LLC /ID# 207237 | Bridgeport | Connecticut | 06606-1827 | — |
| Danbury Clinical Research, LLC /ID# 209517 | Danbury | Connecticut | 06810 | — |
| Arthritis & Osteoporosis Center /ID# 207236 | Hamden | Connecticut | 06518 | — |
| Arthritis & Rheumatic Disease Specialties /ID# 210802 | Aventura | Florida | 33180 | — |
| Rheumatology Associates of South Florida (RASF) - Clinical Research /ID# 211099 | Boca Raton | Florida | 33486 | — |
| SIMED Health, LLC /ID# 207461 | Gainesville | Florida | 32607-2817 | — |
| Sweet Hope Research Specialty Inc /ID# 209393 | Hialeah | Florida | 33016-1897 | — |
| Jacksonville Center for Clinical Research /ID# 209876 | Jacksonville | Florida | 32216 | — |
| Rheum Assoc of Central FL /ID# 201622 | Orlando | Florida | 32806 | — |
| HMD Research LLC /ID# 208427 | Orlando | Florida | 32819 | — |
| IRIS Research and Development, LLC /ID# 208955 | Plantation | Florida | 33324 | — |
| ForCare Clinical Research /ID# 168034 | Tampa | Florida | 33613-1244 | — |
| Arthritis and Rheumatology /ID# 168046 | Atlanta | Georgia | 30342 | — |
| Affinity Clinical Research /ID# 210816 | Oak Brook | Illinois | 60523-1245 | — |
| OrthoIllinois /ID# 205300 | Rockford | Illinois | 61114-4937 | — |
| Springfield Clinic /ID# 200244 | Springfield | Illinois | 62702-3749 | — |
| Klein and Associates MD /ID# 169483 | Hagerstown | Maryland | 21740 | — |
| The Center for Rheumatology and Bone Research /ID# 168017 | Wheaton | Maryland | 20902 | — |
| Clinical Pharmacology Study Gr /ID# 168019 | Worcester | Massachusetts | 01605 | — |
| Advanced Rheumatology, PC /ID# 168042 | Lansing | Michigan | 48910 | — |
| June DO, PC /ID# 208915 | Lansing | Michigan | 48910 | — |
| St. Paul Rheumatology /ID# 208471 | Eagan | Minnesota | 55121 | — |
| Logan Health Research /ID# 213707 | Kalispell | Montana | 59901 | — |
| Physician Research Collaboration, LLC /ID# 208670 | Lincoln | Nebraska | 68516 | — |
| Center for Rheumatology LLP /ID# 207313 | Albany | New York | 12203-3710 | — |
| NYU Langone Ambulatory Care Brooklyn Heights /ID# 207310 | Brooklyn | New York | 11201 | — |
| Joint & Muscle Research Instit /ID# 208620 | Charlotte | North Carolina | 28204 | — |
| Medication Management, LLC /ID# 211734 | Greensboro | North Carolina | 27408 | — |
| Coastal Carolina Health Care /ID# 208619 | New Bern | North Carolina | 28562 | — |
| Velocity Clinical Research /ID# 200452 | Blue Ash | Ohio | 45242-3763 | — |
| Marietta Memorial Hospital /ID# 210179 | Marietta | Ohio | 45750-1635 | — |
| Paramount Medical Research Con /ID# 201583 | Middleburg Heights | Ohio | 44130 | — |
| STAT Research, Inc. /ID# 213805 | Springboro | Ohio | 45066 | — |
| Health Research of Oklahoma /ID# 168027 | Oklahoma City | Oklahoma | 73103-2400 | — |
| Altoona Ctr Clinical Res /ID# 168037 | Duncansville | Pennsylvania | 16635 | — |
| Allegheny Health Network Research Institute /ID# 210349 | Pittsburgh | Pennsylvania | 15212-4756 | — |
| Clinical Research Ctr Reading /ID# 168070 | Wyomissing | Pennsylvania | 19610 | — |
| Nashville Arthritis and Rheumatology /ID# 168069 | Nashville | Tennessee | 37203 | — |
| Amarillo Ctr for Clin Research /ID# 208347 | Amarillo | Texas | 79124 | — |
| Precision Comprehensive Clinical Research Solutions /ID# 208386 | Colleyville | Texas | 76034 | — |
| Dallas VA Medical Center /ID# 208389 | Dallas | Texas | 75216 | — |
| Precision Comprehensive Clinical Research Solutions /ID# 210597 | Fort Worth | Texas | 76107 | — |
| Advanced Rheumatology of Houston /ID# 208354 | The Woodlands | Texas | 77382 | — |
| DM Clinical Research /ID# 208351 | Tomball | Texas | 77375 | — |
| Kadlec Clinic Rheumatology /ID# 207969 | Kennewick | Washington | 99336 | — |
| Rheumatology and Pulmonary Clinic /ID# 200446 | Beckley | West Virginia | 25801 | — |
| Aurora Rheumatology and Immunotherapy Center /ID# 168066 | Franklin | Wisconsin | 53132 | — |
| Holy Family Memorial, Inc. /ID# 209387 | Manitowoc | Wisconsin | 54220 | — |
| Gundersen Clinic, Ltd /ID# 209459 | Onalaska | Wisconsin | 54650 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 197 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03675308, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 5, 2025 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03675308 live on ClinicalTrials.gov.