Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in PGTC Seizures
Public ClinicalTrials.gov record NCT03678753. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Cenobamate Adjunctive Therapy in Subjects With PGTC Seizures
Study identification
- NCT ID
- NCT03678753
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- SK Life Science, Inc.
- Industry
- Enrollment
- 169 participants
Conditions and interventions
Conditions
Interventions
- Cenobamate Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 20, 2018
- Primary completion
- May 25, 2025
- Completion
- May 25, 2025
- Last update posted
- Jul 8, 2025
2018 – 2025
United States locations
- U.S. sites
- 43
- U.S. states
- 26
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| Center for Neurosciences | Tucson | Arizona | 85718 | — |
| Neuro Pain Medical Center | Fresno | California | 93710 | — |
| Colorado Springs Neurological Associates | Colorado Springs | Colorado | 80907 | — |
| Children's Hospital of Colorado | Grand Junction | Colorado | 80045 | — |
| Brainstorm Research | Miami | Florida | 33176 | — |
| Florida Hospital Medical Group | Orlando | Florida | 32803 | — |
| University of South Florida | Tampa | Florida | 33606 | — |
| Clinical Integrative Research Center of Atlanta, CIRCA | Atlanta | Georgia | 30328 | — |
| Children's Healthcare of Atlanta | Atlanta | Georgia | 30329 | — |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | 96814 | — |
| Consultants in Epilepsy and Neurology | Boise | Idaho | 83702 | — |
| Rush University | Chicago | Illinois | 60612 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| PMG Research of McFarland Clinic | Ames | Iowa | 50010 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Maine Medical Center | Scarborough | Maine | 04074 | — |
| Mid-Atlantic Epilepsy and Sleep Center | Bethesda | Maryland | 20817 | — |
| Michigan State University | East Lansing | Michigan | 48824 | — |
| Minneapolis Clinic of Neurology Golden Valley | Golden Valley | Minnesota | 55422 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| University of Missouri Health Care | Columbia | Missouri | 65201 | — |
| JFK Medical Center- The Neuroscience Institute | Edison | New Jersey | 08818 | — |
| Northeast Regional Epilepsy Group | Hackensack | New Jersey | 07601 | — |
| Saint Peter's University Hospital | New Brunswick | New Jersey | 08901 | — |
| New York Presbyterian Hospital | Brooklyn | New York | 11215 | — |
| UBMD Neurology | Buffalo | New York | 14203 | — |
| Five Towns Neuroscience Research | Woodmere | New York | 11598 | — |
| Duke University Children's Health Center | Durham | North Carolina | 27710 | — |
| Ohio Health Research and Innovation Institute | Columbus | Ohio | 43214 | — |
| University of Toledo | Toledo | Ohio | 43606 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Temple University Lewis Katz School of Medicine | Philadelphia | Pennsylvania | 19140 | — |
| LeBonheur Children's Medical Center | Memphis | Tennessee | 38105 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Child Neurology Consultants of Austin | Austin | Texas | 78757 | — |
| ANRC Research | El Paso | Texas | 79912 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Utah / Primary Children's Hospital | Salt Lake City | Utah | 84113 | — |
| Carilion Clinic | Roanoke | Virginia | 24016 | — |
| Valley Medical Center | Renton | Washington | 98057 | — |
| MultiCare Institute for Research and Innovation | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 73 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03678753, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 8, 2025 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03678753 live on ClinicalTrials.gov.