Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain
Public ClinicalTrials.gov record NCT03709901. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain With or Without Intervertebral Disc Herniation - VAST Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to evaluate the safety and efficacy of viable allograft transplantation for the treatment of patients with symptomatic disc degeneration and tissue loss. All subjects randomized to Active Allograft will undergo injection of a viable allograft into the nucleus pulposus of the degenerated disc. All subjects randomized to Placebo will undergo injection with saline into the nucleus pulposus of the degenerated disc. All subjects randomized to Conservative Care will continue standard of care, with the opportunity to crossover at 3 months into the Active Allograft arm.
Study identification
- NCT ID
- NCT03709901
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 218 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 60 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 21, 2017
- Primary completion
- Jan 30, 2022
- Completion
- Jan 30, 2022
- Last update posted
- Jul 6, 2021
2017 – 2022
United States locations
- U.S. sites
- 13
- U.S. states
- 9
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Source Health | Santa Monica | California | 90404 | — |
| IPM Medical Group | Walnut Creek | California | 94598 | — |
| Laser Spine Institute | Tampa | Florida | 33607 | — |
| Athens Orthopedic Clinic | Athens | Georgia | 30606 | — |
| Neurological Institute of Savannah | Savannah | Georgia | 31405 | — |
| OrthoIndy | Indianapolis | Indiana | 46278 | — |
| Michigan Spine Clinic | Brownstown | Michigan | 48183 | — |
| Ainsworth Institute of Pain Management | New York | New York | 10022 | — |
| Clinical Investigations, LLC | Edmond | Oklahoma | 73013 | — |
| Invictus Healthcare | Tulsa | Oklahoma | 74133 | — |
| Texas Back Institute | Plano | Texas | 75093 | — |
| Virginia iSpine Physicians | Richmond | Virginia | 23235 | — |
| Gershon Pain Specialists | Virginia Beach | Virginia | 23454 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03709901, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 6, 2021 · Synced Sep 7, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03709901 live on ClinicalTrials.gov.