Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
Public ClinicalTrials.gov record NCT03715933. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Multicenter, First-in-Human, Phase 1 Dose-Escalation and Multicohort Expansion Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
Study identification
- NCT ID
- NCT03715933
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Inhibrx Biosciences, Inc
- Industry
- Enrollment
- 321 participants
Conditions and interventions
Conditions
Interventions
- Fluorouracil Drug
- INBRX-109 Drug
- Irinotecan Drug
- Leucovorin Drug
- Temozolomide Drug
- carboplatin Drug
- pemetrexed Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 7, 2018
- Primary completion
- May 31, 2026
- Completion
- Nov 30, 2026
- Last update posted
- Mar 17, 2026
2018 – 2026
United States locations
- U.S. sites
- 22
- U.S. states
- 13
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| HonorHealth Research Institute | Scottsdale | Arizona | 85258 | Completed |
| Precision NextGen Oncology and Research | Beverly Hills | California | 90212 | Recruiting |
| City of Hope | Duarte | California | 91010 | Recruiting |
| Valkyrie Clinical Trials | Los Angeles | California | 90067 | Recruiting |
| University of California, San Diego (UCSD) - Moores Cancer Center | San Diego | California | 92093 | Recruiting |
| University of California, San Francisco (UCSF) | San Francisco | California | 94110 | Recruiting |
| Sarcoma Oncology Center | Santa Monica | California | 90403 | Recruiting |
| University of Colorado Hospital | Aurora | Colorado | 80045 | Recruiting |
| Emory University - Winship Cancer Institute | Atlanta | Georgia | 30322 | Recruiting |
| The University of Chicago | Chicago | Illinois | 60637 | Completed |
| University of Michigan | Ann Arbor | Michigan | 48109 | Recruiting |
| START Midwest Michigan, PC | Grand Rapids | Michigan | 49546 | Recruiting |
| David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center | New York | New York | 10021 | Recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Recruiting |
| Oregon Health & Science University | Portland | Oregon | 97239 | Recruiting |
| Children's Hospital of Philadelphia- Center for Childhood Cancer Research | Philadelphia | Pennsylvania | 19104 | Recruiting |
| University of Pennsylvania Abramson Cancer Center | Philadelphia | Pennsylvania | 19106 | Recruiting |
| Vanderbilt University School of Medicine | Nashville | Tennessee | 37232 | Recruiting |
| UT MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| NEXT Oncology | San Antonio | Texas | 78229 | Completed |
| University of Virginia | Charlottesville | Virginia | 22903 | Recruiting |
| NEXT Oncology - Virginia | Fairfax | Virginia | 22031 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03715933, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 17, 2026 · Synced Apr 29, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03715933 live on ClinicalTrials.gov.