Apremilast as a Direct Treatment for Mild-to-moderate Plaque Psoriasis Versus Placebo: an Analysis of Clinical Safety and Efficacy
Public ClinicalTrials.gov record NCT03721172. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Placebo-Controlled, Double-Blind Study of the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Mild to Moderate Plaque Psoriasis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3, multicenter, randomized, placebo-controlled, double-blind study designed to evaluate the efficacy and safety of apremilast (CC-10004) in subjects with mild to moderate plaque psoriasis. Approximately 574 subjects with mild to moderate plaque psoriasis will be randomized 1:1 to receive either apremilast 30 mg BID or placebo for the first 16 weeks.
Study identification
- NCT ID
- NCT03721172
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 595 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 11, 2019 (Actual)
- Primary completion
- Mar 6, 2020 (Actual)
- Completion
- Jul 24, 2020 (Actual)
- Last update posted
- May 29, 2024
2019 – 2020
United States locations
- U.S. sites
- 43
- U.S. states
- 25
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Total Skin & Beauty Dermatology Center | Birmingham | Alabama | 35205 | — |
| Johnson Dermatology Clinic | Fort Smith | Arkansas | 72916 | — |
| Northwest Arkansas Clinical Trials Center, PLLC / Hull Dermatology | Rogers | Arkansas | 72758 | — |
| Dermatology Research Associates | Los Angeles | California | 90045 | — |
| TCR Medical Corporation | San Diego | California | 92123 | — |
| University of California San Francisco Psoriasis and Skin Treatment Center | San Francisco | California | 94118 | — |
| Clinical Science Institute | Santa Monica | California | 90404 | — |
| University of Colorado Hospital - Dermatology Clinic | Aurora | Colorado | 80045 | — |
| Total Vein and Skin, LLC | Boynton Beach | Florida | 33437 | — |
| Florida Academic Centers Research and Education | Coral Gables | Florida | 33134 | — |
| International Dermatology Research | Miami | Florida | 33144 | — |
| Center for Clinical and Cosmetic Research | Miami | Florida | 33180 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| University of South Florida - Carol and Frank Morsani Center for Advanced Health Care | Tampa | Florida | 33612 | — |
| Atlanta Dermatology, Vein and Research Center, PC | Alpharetta | Georgia | 30022 | — |
| Medical Dermatology Specialists, Inc. - Advanced Medical Research | Atlanta | Georgia | 30328 | — |
| MedaPhase INC | Newnan | Georgia | 30263 | — |
| Gwinnett Clinical Research Center, Inc. | Snellville | Georgia | 30078 | — |
| Dawes Fretzin Clinical Research Group, LLC | Indianapolis | Indiana | 46256 | — |
| Clinical Trials Management LLC | Metairie | Louisiana | 70006 | — |
| Derm Associates | Rockville | Maryland | 20850 | — |
| Lawrence Green, MD, LLC | Rockville | Maryland | 20850 | — |
| ActivMed Practices & Research Inc | Beverly | Massachusetts | 01915 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114-2517 | — |
| Henry Ford Medical Center - New Center One | Detroit | Michigan | 48202 | — |
| Minnesota Clinical Study Center | Fridley | Minnesota | 55432 | — |
| Central Dermatology | St Louis | Missouri | 63117 | — |
| JDR Dermatology Research, LLC | Las Vegas | Nevada | 89148 | — |
| Psoriasis Treatment Center of Central New Jersey | East Windsor | New Jersey | 08520 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10003 | — |
| Albert Einstein College of Medicine - Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27104 | — |
| Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Wright State Physicians | Fairborn | Ohio | 45324 | — |
| Temple University - Lewis Katz School of Medicine | Philadelphia | Pennsylvania | 19140 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Clinical Partners, LLC | Johnston | Rhode Island | 02919 | — |
| Clinical Research Center of the Carolinas | Charleston | South Carolina | 29407 | — |
| Austin Institute for Clinical Research | Pflugerville | Texas | 78660 | — |
| Center for Clinical Studies | Webster | Texas | 77598 | — |
| University of Utah MidValley Dermatology | Murray | Utah | 84107 | — |
| Virginia Clinical Research Inc | Norfolk | Virginia | 23502 | — |
| Dermatology Center for Skin Health | Morgantown | West Virginia | 26505 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03721172, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 29, 2024 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03721172 live on ClinicalTrials.gov.