Efficacy, Safety, and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis.
Public ClinicalTrials.gov record NCT03747939. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 4, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Early, Oligoarticular Psoriatic Arthritis Despite Initial Stable Treatment With Either NSAIDS and/or ≤ 1 Conventional Synthetic DMARD
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This clinical study will test the effects of a drug called apremilast in oligoarticular psoriatic arthritis with less than 5 years of disease duration. In previous studies, apremilast has been shown to be safe and efficacious in reducing signs and symptoms of psoriatic arthritis, as well as improving physical function. This study will compare the effects of apremilast to placebo on psoriatic arthritis subjects in which the number of affected joints is limited (greater than 1 but less or equal to 4). About 285 patients worldwide will take part in this study.
Study identification
- NCT ID
- NCT03747939
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 310 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2018 (Actual)
- Primary completion
- Dec 19, 2022 (Actual)
- Completion
- Jul 5, 2023 (Actual)
- Last update posted
- Sep 11, 2026
2018 – 2023
United States locations
- U.S. sites
- 54
- U.S. states
- 24
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Arthritis and Rheumatology Research, PLLC | Mesa | Arizona | 85202 | — |
| Covina Arthritis Clinic | Covina | California | 91722 | — |
| Encino Research Center | Encino | California | 91436 | — |
| Providence Medical Foundation | Fullerton | California | 92835 | — |
| Rheumatology Center of San Diego PC | San Diego | California | 92128 | — |
| East Bay Rheumatology Medical | San Leandro | California | 94578 | — |
| Millennium Clinical Trials | Thousand Oaks | California | 91360 | — |
| Robin K Dore MD Inc | Tustin | California | 92780 | — |
| Inland Rheumatology Clinical Trials Inc | Upland | California | 91786 | — |
| Denver Arthritis Clinic PC | Denver | Colorado | 80230 | — |
| Arthritis and Rheumatic Disease Specialties | Aventura | Florida | 33180 | — |
| Clinical Research of West Florida, Inc | Clearwater | Florida | 33765 | — |
| Center for Rheumatology, Immunology, and Arthritis | Fort Lauderdale | Florida | 33309 | — |
| University of Florida College of Medicine | Gainesville | Florida | 32610 | — |
| Integral Rheumatology and Immunology Specialists | Plantation | Florida | 33324 | — |
| Florida Center For Dermatology | Saint Augustine | Florida | 32080 | — |
| Clinical Research of West Florida Inc | Tampa | Florida | 33606-1246 | — |
| Carol and Frank Morsani Center for Advanced Health Care | Tampa | Florida | 33612 | — |
| Baycare Medical Group Inc | Tampa | Florida | 33614 | — |
| North Georgia Rheumatology Group PC | Lawrenceville | Georgia | 30046 | — |
| RC Rsearch Inc | Hinsdale | Illinois | 60521 | — |
| OrthoIllinois | Rockford | Illinois | 61114 | — |
| Graves Gilbert Clinic | Bowling Green | Kentucky | 42101 | — |
| Clinical Trials Management LLC | Metairie | Louisiana | 70006 | — |
| Klein and Associates MD, PA - Cumberland | Cumberland | Maryland | 21502 | — |
| Klein and Associates MD PA | Hagerstown | Maryland | 21740 | — |
| Clinical Pharmacology Study Group | Worcester | Massachusetts | 01605 | — |
| Advanced Rheumatology PC | Lansing | Michigan | 48910 | — |
| Arthritis and Rheumatology Center of Michigan | Lansing | Michigan | 48910 | — |
| Clinical Research Institute of Michigan | Saint Clair Shores | Michigan | 48081 | — |
| Saint Paul Rheumatology PA | Eagan | Minnesota | 55121 | — |
| Arthritis, Rheumatic, and Back Disease Associates | Voorhees Township | New Jersey | 08043 | — |
| New York University Langone Medical Center | New York | New York | 10003 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Joint and Muscle Research Institute | Charlotte | North Carolina | 28204 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Paramount Medical Research and Consulting LLC | Middleburg Heights | Ohio | 44130 | — |
| Arthritis and Osteoporosis Center of Southwest Ohio | Middletown | Ohio | 45044 | — |
| Health Research of Oklahoma | Oklahoma City | Oklahoma | 73103 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Arthritis Group | Philadelphia | Pennsylvania | 19152 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Piedmont Arthritis Clinic | Greenville | South Carolina | 29601 | — |
| West Tennessee Research Institute, llc | Jackson | Tennessee | 38305 | — |
| Accurate Clinical Research Incorporated Baytown | Baytown | Texas | 77521 | — |
| Precision Comprehensive Clinical Research Solutions | Colleyville | Texas | 76034 | — |
| Texas Arthritis Center PA | El Paso | Texas | 79902 | — |
| West Texas Clinical Research | Lubbock | Texas | 79410 | — |
| Advanced Rheumatology of Houston | The Woodlands | Texas | 77382 | — |
| Center for Clinical Studies | Webster | Texas | 92103 | — |
| Seattle Rheumatology Associates | Seattle | Washington | 98104 | — |
| Rheumatology and Pulmonary Clinic | Beckley | West Virginia | 25801 | — |
| West Virginia Research Institute | Morgantown | West Virginia | 26505 | — |
| West Virginia Research Institute | South Charleston | West Virginia | 25309 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 60 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03747939, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 11, 2026 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03747939 live on ClinicalTrials.gov.