ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

Tislelizumab in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable, Locally Advanced or Metastatic Gastric, or Gastroesophageal Junction Carcinoma

ClinicalTrials.gov ID: NCT03777657

Public ClinicalTrials.gov record NCT03777657. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 16, 2026, 8:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Clinical Study Comparing the Efficacy and Safety of Tislelizumab (BGB-A317) Plus Platinum and Fluoropyrimidine Versus Placebo Plus Platinum and Fluoropyrimidine as First-Line Treatment in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Study identification

NCT ID
NCT03777657
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
BeiGene
Industry
Enrollment
997 participants

Conditions and interventions

Interventions

  • 5-Fluorouracil Drug
  • Capecitabine Drug
  • Cisplatin Drug
  • Oxaliplatin Drug
  • Placebo Drug
  • Tislelizumab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 12, 2018
Primary completion
Feb 27, 2023
Completion
Aug 26, 2024
Last update posted
Feb 13, 2025

2018 – 2024

United States locations

U.S. sites
6
U.S. states
5
U.S. cities
6
Facility City State ZIP Site status
University of California Davis Health System Sacramento California 95817
Southeastern Regional Medical Center Newnan Georgia 30265
Ohio State University Hospital Columbus Ohio 43210
Fox Chase Cancer Center Philadelphia Pennsylvania 19111
Reading Hospital West Reading Pennsylvania 19611
Tennessee Oncology, Pllc Nashville Nashville Tennessee 37203

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 143 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03777657, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 13, 2025 · Synced May 16, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03777657 live on ClinicalTrials.gov.

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