Durvalumab Alone or in Combination With Novel Agents in Subjects With NSCLC
Public ClinicalTrials.gov record NCT03822351. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Open-label, Multicenter, Randomized, Multidrug Platform Study of Durvalumab (MEDI4736) Alone or in Combination With Novel Agents in Subjects With Locally Advanced, Unresectable (Stage III) Non-small Cell Lung Cancer (COAST)
Study identification
- NCT ID
- NCT03822351
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- MedImmune LLC
- Industry
- Enrollment
- 189 participants
Conditions and interventions
Conditions
Interventions
- Durvalumab Drug
- Durvalumab + Monalizumab Drug
- Durvalumab + Oleclumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 18, 2018
- Primary completion
- Jul 17, 2023
- Completion
- Jul 17, 2023
- Last update posted
- Oct 7, 2024
2018 – 2023
United States locations
- U.S. sites
- 28
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Anaheim | California | 92801 | — |
| Research Site | Duarte | California | 91010 | — |
| Research Site | Sacramento | California | 95825 | — |
| Research Site | New Haven | Connecticut | 06510 | — |
| Research Site | West Haven | Connecticut | 06516 | — |
| Research Site | Washington D.C. | District of Columbia | 20007 | — |
| Research Site | Orlando | Florida | 32804 | — |
| Research Site | Winter Haven | Florida | 33881 | — |
| Research Site | Wichita | Kansas | 67214 | — |
| Research Site | Lexington | Kentucky | 40503 | — |
| Research Site | Louisville | Kentucky | 40202 | — |
| Research Site | Baton Rouge | Louisiana | 70809 | — |
| Research Site | Covington | Louisiana | 70433 | — |
| Research Site | Rosedale | Maryland | 21237 | — |
| Research Site | Lincoln | Nebraska | 68510 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | New York | New York | 10065 | — |
| Research Site | Portland | Oregon | 97227-1191 | — |
| Research Site | Gettysburg | Pennsylvania | 17325 | — |
| Research Site | Lancaster | Pennsylvania | 17601 | — |
| Research Site | Philadelphia | Pennsylvania | 19104 | — |
| Research Site | Sioux Falls | South Dakota | 57105 | — |
| Research Site | Germantown | Tennessee | 38138 | — |
| Research Site | Memphis | Tennessee | 38120 | — |
| Research Site | Tyler | Texas | 75701 | — |
| Research Site | Salt Lake City | Utah | 84112 | — |
| Research Site | Richmond | Virginia | 23230 | — |
| Research Site | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03822351, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 7, 2024 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03822351 live on ClinicalTrials.gov.