A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (TENAYA)
Public ClinicalTrials.gov record NCT03823287. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicenter, Randomized, Double-Masked, Active Comparator-Controlled Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Neovascular Age-Related Macular Degeneration (TENAYA)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy, safety, durability, and pharmacokinetics of faricimab administered at intervals as specified in the protocol, compared with aflibercept once every 8 weeks (Q8W), in participants with neovascular age-related macular degeneration (nAMD).
Study identification
- NCT ID
- NCT03823287
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 671 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 19, 2019 (Actual)
- Primary completion
- Oct 26, 2020 (Actual)
- Completion
- Jan 18, 2022 (Actual)
- Last update posted
- Jul 23, 2025
2019 – 2022
United States locations
- U.S. sites
- 52
- U.S. states
- 24
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Research Institute, LLC | Phoenix | Arizona | 85014 | — |
| Barnet Dulaney Perkins Eye Center | Phoenix | Arizona | 85016 | — |
| Retina Associates Southwest PC | Tucson | Arizona | 85704 | — |
| Retinal Diagnostic Center | Campbell | California | 95008 | — |
| The Retina Partners | Encino | California | 91436 | — |
| Jacobs Retina center at the Shiley eye Institute UCSD | La Jolla | California | 92093 | — |
| South Coast Retina Center | Long Beach | California | 90807 | — |
| Southern CA Desert Retina Cons | Palm Desert | California | 92211 | — |
| California Eye Specialists Medical group Inc. | Pasadena | California | 91107 | — |
| Retina Consultants, San Diego | Poway | California | 92064 | — |
| Retina Consultants of Southern California | Redlands | California | 92373 | — |
| University of California, Davis, Eye Center | Sacramento | California | 95817 | — |
| Retina Consultants of Southern | Colorado Springs | Colorado | 80909 | — |
| Retina Group of New England | New London | Connecticut | 06320 | — |
| Rand Eye | Deerfield Beach | Florida | 33064 | — |
| Florida Eye Associates | Melbourne | Florida | 32901 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Fort Lauderdale Eye Institute | Plantation | Florida | 33324 | — |
| Retina Vitreous Assoc of FL | St. Petersburg | Florida | 33711 | — |
| Northwestern Medical Group/Northwestern University | Chicago | Illinois | 60611 | — |
| Retina Associates | Lenexa | Kansas | 66215 | — |
| Johns Hopkins Med | Baltimore | Maryland | 21287 | — |
| Retina Group of Washington | Chevy Chase | Maryland | 20815 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Associated Retinal Consultants | Grand Rapids | Michigan | 49546 | — |
| Midwest Vision Research Foundation | Chesterfield | Missouri | 63017 | — |
| Retina Associates of St. Louis | Florissant | Missouri | 63031 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| NJ Retina | Edison | New Jersey | 08820 | — |
| Retina Associates of NJ | Teaneck | New Jersey | 07666 | — |
| Long Is. Vitreoretinal Consult | Great Neck | New York | 11021 | — |
| Ophthalmic Cons of Long Island | Oceanside | New York | 11572 | — |
| Retina Assoc of Western NY | Rochester | New York | 14620 | — |
| The Retina Consultants | Slingerlands | New York | 12159 | — |
| Retina Vit Surgeons/Central NY | Syracuse | New York | 13224 | — |
| Western Carolina Retinal Associate PA | Asheville | North Carolina | 28803 | — |
| Char Eye Ear &Throat Assoc | Charlotte | North Carolina | 28210 | — |
| Graystone Eye | Hickory | North Carolina | 28602 | — |
| Carolina Eye Associates | Southern Pines | North Carolina | 28387 | — |
| Cincinnati Eye Institute | Cincinnati | Ohio | 45242 | — |
| Retina Northwest | Portland | Oregon | 97221 | — |
| Mid Atlantic Retina - Wills Eye Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Charleston Neuroscience Inst | Ladson | South Carolina | 29456 | — |
| Black Hills Eye Institute | Rapid City | South Dakota | 57701 | — |
| Charles Retina Institute | Germantown | Tennessee | 38138 | — |
| Tennessee Retina PC. | Nashville | Tennessee | 37203 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
| Retina & Vitreous of Texas | Houston | Texas | 77025 | — |
| Retina Consultants of Texas | Houston | Texas | 77030 | — |
| Valley Retina Institute P.A. | McAllen | Texas | 78503 | — |
| Rocky Mountain Retina | Salt Lake City | Utah | 84107 | — |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 109 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03823287, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 23, 2025 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03823287 live on ClinicalTrials.gov.