Basket Trial in Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3- (FUZE Clinical Trial)
Public ClinicalTrials.gov record NCT03834220. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Basket Study of the Oral Selective Pan-FGFR Inhibitor Debio 1347 in Subjects With Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to assess the efficacy of Debio 1347 in terms of objective response rate (ORR) in participants with solid tumors harboring fibroblast growth factor receptor (FGFR)1-3 gene fusion/rearrangement.
Study identification
- NCT ID
- NCT03834220
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 63 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 22, 2019 (Actual)
- Primary completion
- Dec 31, 2020 (Actual)
- Completion
- Jan 4, 2022 (Actual)
- Last update posted
- Feb 7, 2024
2019 – 2022
United States locations
- U.S. sites
- 25
- U.S. states
- 18
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ironwood Cancer & Research Centers - Scottsdale | Scottsdale | Arizona | 85260 | — |
| University of Arizona Cancer Center | Tucson | Arizona | 85721 | — |
| Moores UCSD Cancer Center | La Jolla | California | 92093 | — |
| University of California San Francisco | San Francisco | California | 94115 | — |
| Sarcoma Oncology Center | Santa Monica | California | 90403 | — |
| H. Lee Moffitt Cancer Center and Research Institute, Inc | Tampa | Florida | 33612 | — |
| James Graham Brown Cancer Center | Louisville | Kentucky | 10202 | — |
| Tulane University Cancer Center | New Orleans | Louisiana | 70122 | — |
| The John Hopkins Hospital | Baltimore | Maryland | 21231 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Memorial Sloan Kettering Cancer Center | Middletown | New Jersey | 07748 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| Memorial Sloan Kettering Cancer Center | Harrison | New York | 10604 | — |
| Memorial Sloan-Kettering Hospital | New York | New York | 10065 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| UC Health, LLC. | Cincinnati | Ohio | 45229 | — |
| The Ohio State University Wexner Medical Center - James Cancer Hospital | Columbus | Ohio | 43210 | — |
| CTCA Cancer Treatment Centers | Tulsa | Oklahoma | 74133 | — |
| West Penn - Allegheny Oncology Network | Pittsburgh | Pennsylvania | 15224 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| University of Utah Hospitals & Clinics | Salt Lake City | Utah | 84108 | — |
| Fred Hutchinson/Seattle Care Alliance | Seattle | Washington | 98109 | — |
| University of Wisconsin | Madison | Wisconsin | 53706 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 80 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03834220, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 7, 2024 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03834220 live on ClinicalTrials.gov.