Assess Efficacy and Safety of Durvalumab Alone or Combined With Bevacizumab in High Risk of Recurrence HCC Patients After Curative Treatment
Public ClinicalTrials.gov record NCT03847428. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multi Center Study of Durvalumab Monotherapy or in Combination With Bevacizumab as Adjuvant Therapy in Patients With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A global study to assess the efficacy and safety of durvalumab in combination with bevacizumab or durvalumab alone in patients with hepatocellular carcinoma who are at high risk of recurrence.
Study identification
- NCT ID
- NCT03847428
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 908 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 150 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 28, 2019
- Primary completion
- May 14, 2026
- Completion
- May 30, 2027
- Last update posted
- Aug 13, 2026
2019 – 2027
United States locations
- U.S. sites
- 34
- U.S. states
- 23
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35233 | — |
| Research Site | Mobile | Alabama | 36604 | — |
| Research Site | Phoenix | Arizona | 85054 | — |
| Research Site | Costa Mesa | California | 92627 | — |
| Research Site | La Jolla | California | 92093-0698 | — |
| Research Site | Long Beach | California | 90806 | — |
| Research Site | Orange | California | 92868 | — |
| Research Site | Sacramento | California | 95817 | — |
| Research Site | Washington D.C. | District of Columbia | 20007 | — |
| Research Site | Miami | Florida | 33176 | — |
| Research Site | Tampa | Florida | 33606 | — |
| Research Site | Honolulu | Hawaii | 96819 | — |
| Research Site | Chicago | Illinois | 60637 | — |
| Research Site | Westwood | Kansas | 66205 | — |
| Research Site | Louisville | Kentucky | 40206 | — |
| Research Site | Shreveport | Louisiana | 71103 | — |
| Research Site | Detroit | Michigan | 48201 | — |
| Research Site | Grand Rapids | Michigan | 49503 | — |
| Research Site | Rochester | Minnesota | 55905 | — |
| Research Site | Omaha | Nebraska | 68198 | — |
| Research Site | New Brunswick | New Jersey | 08903 | — |
| Research Site | Albuquerque | New Mexico | 87109 | — |
| Research Site | New York | New York | 10021 | — |
| Research Site | Stony Brook | New York | 11794 | — |
| Research Site | Durham | North Carolina | 27710 | — |
| Research Site | Winston-Salem | North Carolina | 27157 | — |
| Research Site | Cleveland | Ohio | 44106 | — |
| Research Site | Philadelphia | Pennsylvania | 19104 | — |
| Research Site | Pittsburgh | Pennsylvania | 15212 | — |
| Research Site | Spartanburg | South Carolina | 29303 | — |
| Research Site | Knoxville | Tennessee | 37916 | — |
| Research Site | Memphis | Tennessee | 38104 | — |
| Research Site | Dallas | Texas | 75216 | — |
| Research Site | Madison | Wisconsin | 53715 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 183 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03847428, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 13, 2026 · Synced Sep 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03847428 live on ClinicalTrials.gov.