ClinicalTrials.gov record
Active, not recruiting Phase 2 Interventional Results available

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

ClinicalTrials.gov ID: NCT03849651

Public ClinicalTrials.gov record NCT03849651. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 7:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Study identification

NCT ID
NCT03849651
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
St. Jude Children's Research Hospital
Other
Enrollment
69 participants

Conditions and interventions

Interventions

  • ATG (rabbit) Biological
  • Blinatumomab Drug
  • CD19+ Biological
  • CD45RA-depleted DLI Biological
  • CliniMACS Device
  • Cyclophosphamide Drug
  • Fludarabine Biological
  • G-csf Biological
  • Melphalan Drug
  • Mesna Drug
  • TCRα/β+ Biological
  • Thiotepa Drug

Biological · Drug · Device

Eligibility (public fields only)

Age range
Up to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 30, 2019
Primary completion
Aug 6, 2024
Completion
Jun 6, 2026
Last update posted
Apr 12, 2026

2019 – 2026

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
St. Jude Children's Research Hospital Memphis Tennessee 38105

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03849651, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 12, 2026 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03849651 live on ClinicalTrials.gov.

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