Study of Post-Herniorrhaphy Non-opioid MMA Regimens
Public ClinicalTrials.gov record NCT03907176. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b, Randomized, Open-Label Study of HTX-011 as the Foundation of a Non-opioid, Multimodal Analgesic Regimen to Decrease Opioid Use Following Unilateral Open Inguinal Herniorrhaphy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3b, open-label study to assess postoperative opioid use in subjects undergoing unilateral open inguinal herniorrhaphy with intraoperative administration of HTX-011 and a postoperative non-opioid multimodal analgesic (MMA) regimen. The study will be conducted in 2 sequential parts: Part 1 is randomized and Part 2 is Investigator's preference for MMA regimen.
Study identification
- NCT ID
- NCT03907176
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 209 participants
Conditions and interventions
Conditions
Interventions
- HTX-011 Drug
- Luer lock applicator Device
- Ibuprofen Drug
- Acetaminophen Drug
Drug · Device
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 4, 2019 (Actual)
- Primary completion
- Oct 25, 2021 (Actual)
- Completion
- Nov 22, 2021 (Actual)
- Last update posted
- Jun 4, 2026
2019 – 2021
United States locations
- U.S. sites
- 30
- U.S. states
- 13
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Anaheim Clinical Trials, LLC | Anaheim | California | 92801 | — |
| Horizon Clinical Research | La Mesa | California | 91942 | — |
| Sharp Grossmont Hospital | La Mesa | California | 91942 | — |
| University of California, Irvine Medical Center | Orange | California | 92868 | — |
| Parkview Community Hospital | Riverside | California | 92503 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | — |
| Medical Research of Westchester, Inc | Miami | Florida | 33144 | — |
| Professional Health Care of Pinellas | St. Petersburg | Florida | 33713 | — |
| University of Louisville Hospital | Louisville | Kentucky | 40202 | — |
| Baylor University Medical Center | Dallas | Missouri | 75246 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Rutgers - New Jersey Medical School | Newark | New Jersey | 07103 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11794 | — |
| Montefiore Hutchinson Campus | The Bronx | New York | 10461 | — |
| M3 Emerging Medical Research, LLC | Durham | North Carolina | 27704 | — |
| Cleveland Clinic Fairview | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University Wexner Medical Center - University Hospital | Columbus | Ohio | 43210 | — |
| Midwest Clinical Research Center, LLC | Dayton | Ohio | 45417 | — |
| Summit Medical Group Oregon-Bend Memorial Clinic | Bend | Oregon | 97701 | — |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| UPMC Shadyside Hospital | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC Passavant | Pittsburgh | Pennsylvania | 15237 | — |
| Baylor University Medical Center | Dallas | Texas | 75246 | — |
| Hermann Drive Surgical Hospital | Houston | Texas | 77004 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Plano Surgical Hospital | Plano | Texas | 75093 | — |
| Endeavor Clinical Trials, LLC | San Antonio | Texas | 78229 | — |
| JBR Clinical Research | Draper | Utah | 84020 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03907176, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 4, 2026 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03907176 live on ClinicalTrials.gov.