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Completed Phase 4 Interventional Results available

Study of Sustained Benefit of AMG334 in Adult Episodic Migraine Patients

ClinicalTrials.gov ID: NCT03927144

Public ClinicalTrials.gov record NCT03927144. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 11:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 12-month Prospective, Randomized, Interventional, Global, Multi-center, Active-controlled Study Comparing Sustained Benefit of Two Treatment Paradigms (AMG334 qm vs. Oral Prophylactics) in Adult Episodic Migraine Patients

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to compare the sustained long-term benefit between two treatment paradigms of migraine prophylactic agents (erenumab versus a control arm of oral prophylactics) in episodic migraine patients who have previously failed 1 to 2 prophylactic migraine treatments.

Study identification

NCT ID
NCT03927144
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
Amgen
Industry
Enrollment
621 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 15, 2019 (Actual)
Primary completion
Oct 1, 2021 (Actual)
Completion
Sep 30, 2022 (Actual)
Last update posted
Nov 18, 2023

2019 – 2022

United States locations

U.S. sites
20
U.S. states
14
U.S. cities
20
Facility City State ZIP Site status
Stanford Headache Center Stanford California 94305 —
Yale Center for Clinical Research New Haven Connecticut 06519 —
New England Institute for Neurology and Headache Stamford Connecticut 06905 —
George Washington Hospital Washington D.C. District of Columbia 20037 —
University of Miami Headache Division Miami Florida 33136 —
Premier Research Institute West Palm Beach Florida 33407 —
Diamond Headache Clinic Chicago Illinois 60642 —
Robbins Headache Clinic Riverwoods Illinois 60015 —
Medvadis Watertown Massachusetts 02472 —
New England Regional Headache Center, Inc Worcester Massachusetts 01605 —
MHNI Ann Arbor Michigan 48104 —
Clinical Research Institute Minneapolis Minnesota 55402 —
The Headache Center Ridgeland Mississippi 38157 —
Study Metrix Research City of Saint Peters Missouri 63303 —
Mercy Health Research St Louis Missouri 63141 —
Laszlo Mechtler Amherst New York 14226 —
Jefferson Headache Center Philadelphia Pennsylvania 19107 —
Nashville Neuroscience Group Nashville Tennessee 37203 —
Texas Neurology Dallas Texas 75214 —
Texas Institute for Neurological Disorders Sherman Texas 75092 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 92 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03927144, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 18, 2023 · Synced Oct 24, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03927144 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →