UNLOCKED: A Phase 2, Open-label Trial With KB195 in Subjects With a Urea Cycle Disorder

ClinicalTrials.gov ID: NCT03933410

Public ClinicalTrials.gov record NCT03933410. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 22, 2026, 1:01 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Open-label Study to Evaluate the Efficacy and Safety of KB195 in Subjects With A Urea Cycle Disorder With Inadequate Control on Standard of Care

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

UNLOCKED: A Phase 2 Trial to Evaluate the Efficacy and Safety of KB195 in Subjects with a Urea Cycle Disorder with Inadequate Control on Standard of Care

Study identification

NCT ID: NCT03933410
Recruitment status: Terminated
Study type: Interventional
Phase: Phase 2
Lead sponsor: Kaleido Biosciences; Industry
Enrollment: 13 participants

Conditions and interventions

Conditions

Urea Cycle Disorder

Interventions

KB195 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 65 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Sep 17, 2019 (Actual)
Primary completion: Feb 2, 2021 (Actual)
Completion: Mar 2, 2021 (Actual)
Last update posted: Jan 25, 2022

2019 – 2021

United States locations

U.S. sites: 6
U.S. states: 6
U.S. cities: 6

Facility	City	State	ZIP	Site status
Children's National Medical Center	Washington D.C.	District of Columbia	20010	—
University of South Florida/ USF HEALTH	Tampa	Florida	33606	—
Johns Hopkins University School of Medicine	Baltimore	Maryland	12105	—
Washington University School of Medicine	St Louis	Missouri	63110	—
Icahn School of Medicine at Mount Sinai-Clinical Research Unit	New York	New York	10029	—
UPMC Children's Hospital of Pittsburgh	Pittsburgh	Pennsylvania	15224	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT03933410, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jan 25, 2022 · Synced Oct 22, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03933410 live on ClinicalTrials.gov.

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