Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

ClinicalTrials.gov ID: NCT03947385

Public ClinicalTrials.gov record NCT03947385. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search

ClinicalTrials.gov public records Last synced May 5, 2026, 10:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

Study identification

NCT ID: NCT03947385
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1, Phase 2
Lead sponsor: IDEAYA Biosciences; Industry
Enrollment: 336 participants

Conditions and interventions

Conditions

Interventions

Binimetinib Drug
Crizotinib Drug
IDE196 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 27, 2019
Primary completion: Jan 28, 2027
Completion: Jun 14, 2027
Last update posted: Jan 26, 2026

2019 – 2027

United States locations

U.S. sites: 12
U.S. states: 10
U.S. cities: 12

Facility	City	State	ZIP	Site status
UCLA Medical Center	Los Angeles	California	90095	Recruiting
San Francisco Oncology Associates	San Francisco	California	94115	Active, not recruiting
SCRI - Denver	Denver	Colorado	80218	Recruiting
University of Iowa	Iowa City	Iowa	52242	Active, not recruiting
Cancer Hematology Centers Western Michigan	Grand Rapids	Michigan	49503	Active, not recruiting
Columbia University Medical Center - Herbert Irving Pavilion	New York	New York	10032	Active, not recruiting
Duke University Medical Center	Durham	North Carolina	27710	Recruiting
University of Cincinnati Cancer Center	Cincinnati	Ohio	45267	Recruiting
The Cleveland Clinic Foundation	Cleveland	Ohio	44195	Active, not recruiting
Sidney Kimmel Cancer Center at Thomas Jefferson University	Philadelphia	Pennsylvania	19107	Recruiting
The Sarah Cannon Research Institute/Tennessee Oncology	Nashville	Tennessee	37203	Recruiting
The University of Texas MD Anderson Cancer Center	Houston	Texas	77030	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT03947385, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jan 26, 2026 · Synced May 5, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03947385 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →