A Depot Formulation of Sunitinib Malate (GB-102) Compared to Aflibercept in Subjects With Wet AMD
Public ClinicalTrials.gov record NCT03953079. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b Multicenter Dose-Ranging Study Evaluating the Safety and Efficacy of Sunitinib Malate Depot Formulation (GB-102) Compared to Aflibercept in Subjects With Neovascular (Wet) Age-related Macular Degeneration (ALTISSIMO Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Phase 2b, multicenter, visual examiner-masked, randomized active-controlled, parallel-arm design study to evaluate the safety and duration of repeated IVT injections of 3 dose levels of GB-102 compared with aflibercept.
Study identification
- NCT ID
- NCT03953079
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 56 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 26, 2019 (Actual)
- Primary completion
- Dec 15, 2020 (Actual)
- Completion
- Jun 3, 2021 (Actual)
- Last update posted
- Jan 19, 2022
2019 – 2021
United States locations
- U.S. sites
- 33
- U.S. states
- 16
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Consultants AZ | Gilbert | Arizona | 85296 | — |
| Retinal Research Institute | Phoenix | Arizona | 85017 | — |
| California Retina Research Consultants | Bakersfield | California | 93309 | — |
| Retinal Diagnostic Center of Northern California | Campbell | California | 95008 | — |
| The Retina Partners | Encino | California | 91436 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| Northern California Retina Vitreous Associates Medical Group, Inc. | Mountain View | California | 94040 | — |
| West Coast Retina Medical Group, Inc. | San Francisco | California | 94109 | — |
| California Retina Consultants - CRC | Santa Barbara | California | 93103 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| Specialty Retina Center | Coral Springs | Florida | 32503 | — |
| Florida Retina Institute | Orlando | Florida | 32806-1101 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Eye Associates of Pinellas | Pinellas Park | Florida | 33782 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Retina Consultants of Hawaii | ‘Aiea | Hawaii | 96701 | — |
| University Retina and Macula | Lemont | Illinois | 60439 | — |
| Wolfe Eye Clinic - West Des Moines | Des Moines | Iowa | 50266 | — |
| Eye Associates of Northeast Louisiana | West Monroe | Louisiana | 71291 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Mid Atlantic Retina Specialists | Hagerstown | Maryland | 21740 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Ophthalmic Consultants of Long Island | Oceanside | New York | 11572 | — |
| Sterling Research | Cincinnati | Ohio | 45219 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Retina Research Center, PLLC | Austin | Texas | 78705 | — |
| Retina Specialists | Plano | Texas | 75093 | — |
| Retina Consultants of Houston | The Woodlands | Texas | 77384 | — |
| Strategic Clinical Research Group LLC | Willow Park | Texas | 76087 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
| Retina Center NW PLLC | Silverdale | Washington | 98383 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03953079, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 19, 2022 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03953079 live on ClinicalTrials.gov.