Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
ClinicalTrials.gov record
Recruiting Phase 2Phase 3 Interventional

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

ClinicalTrials.gov ID: NCT03970447

Public ClinicalTrials.gov record NCT03970447. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search
ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:40 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

GBM AGILE: Global Adaptive Trial Master Protocol: An International, Seamless Phase II/III Response Adaptive Randomization Platform Trial Designed To Evaluate Multiple Regimens In Newly Diagnosed and Recurrent GBM

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/III response adaptive randomization platform trial designed to evaluate multiple therapies in newly diagnosed (ND) and recurrent GBM. All institutions are enrolling Newly Diagnosed participants. Institutions also enrolling Recurrent participants are marked with an asterisk (\*).

Study identification

NCT ID
NCT03970447
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2, Phase 3
Enrollment
2,250 participants

Conditions and interventions

Conditions

Interventions

Drug · Radiation · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 29, 2019
Primary completion
May 31, 2028
Completion
May 31, 2030
Last update posted
Jul 29, 2026

2019 – 2030

United States locations

U.S. sites
42
U.S. states
22
U.S. cities
34
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35249 Recruiting
University of California, San Diego La Jolla California 92093 Recruiting
Cedars Sinai - Samuel Oschin Comprehensive Cancer Institute Los Angeles California 90048 Recruiting
University of California, Los Angeles Los Angeles California 90095 Active, not recruiting
St. Joseph Hospital Orange California 92868 Recruiting
University of California, San Francisco San Francisco California 94143 Active, not recruiting
Stanford Cancer Center Stanford California 94305 Completed
University of Colorado Denver Aurora Colorado 80045 Recruiting
Yale Cancer Center / Smilow Cancer Hospital* New Haven Connecticut 06511 Recruiting
Mayo Clinic Cancer Center Jacksonville Florida 32224 Completed
Sylvester Comprehensive Cancer Center* Miami Florida 33136 Recruiting
Moffitt Cancer Center Tampa Florida 33612 Active, not recruiting
Piedmont Atlanta Hospital Atlanta Georgia 30309 Active, not recruiting
Winship Cancer Institute of Emory University Atlanta Georgia 30322 Completed
LSU Health Sciences Center - New Orleans New Orleans Louisiana 70112 Completed
Massachusetts General Hospital Boston Massachusetts 02114 Recruiting
Dana Farber Cancer Institute Boston Massachusetts 02115 Recruiting
Henry Ford Health System Detroit Michigan 48202 Completed
Allina Health Systems/Abbott Northwestern Hospital Minneapolis Minnesota 55407 Recruiting
Mayo Clinic Cancer Center - Rochester Rochester Minnesota 55905 Completed
University of Mississippi Medical Center Jackson Mississippi 39213 Completed
Washington University School of Medicine - Siteman Cancer Center St Louis Missouri 63110 Completed
Perlmutter Cancer Center, NYU Langone Health New York New York 10016 Active, not recruiting
Icahn School of Medicine at Mount Sinai New York New York 10029 Recruiting
Columbia University Medical Center New York New York 10032 Recruiting
Memorial Sloan Kettering Cancer Center* New York New York 10065 Recruiting
Duke University Medical Center Durham North Carolina 27710 Active, not recruiting
Comprehensive Cancer Center of Wake Forest* Winston-Salem North Carolina 272157 Recruiting
University Hospitals Cleveland Medical Center* Cleveland Ohio 44106 Recruiting
Cleveland Clinic Cleveland Ohio 44195 Recruiting
Ohio State University Cancer Center Columbus Ohio 43210 Active, not recruiting
University of Pennsylvania - Perelman Center for Advanced Medicine Philadelphia Pennsylvania 19104 Active, not recruiting
Allegheny General Hospital Pittsburgh Pennsylvania 15212 Completed
University of Pittsburgh Medical Center - Hillman Cancer Center Pittsburgh Pennsylvania 15232 Recruiting
Medical University of South Carolina - Hollings Cancer Center Charleston South Carolina 29425 Recruiting
Texas Oncology - Austin Austin Texas 78705 Active, not recruiting
University of Texas Southwestern Medical Center Dallas Texas 75390 Active, not recruiting
University of Texas - MD Anderson Cancer Center Houston Texas 77030 Recruiting
University of Utah - Huntsman Cancer Institute Salt Lake City Utah 84112 Recruiting
University of Virginia Health Charlottesville Virginia 22908 Recruiting
University of Washington Medical Center Seattle Washington 98101 Active, not recruiting
Froedtert Hospital/Medical College of Wisconsin Milwaukee Wisconsin 53226 Active, not recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03970447, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 29, 2026 · Synced Sep 2, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03970447 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →