A Study of Abemaciclib (LY2835219) in Participants With HR+, HER2- Advanced Breast Cancer
Public ClinicalTrials.gov record NCT03988114. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Single-Arm, Global, Phase 4 Study of Abemaciclib, a CDK 4 & 6 Inhibitor, in Combination With Nonsteroidal Aromatase Inhibitors (Anastrozole or Letrozole) in Participants With Hormone Receptor Positive, Human Epidermal Growth Factor Receptor 2 Negative Advanced Breast Cancer With Poor Prognostic Factors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The reason for this study is to see if the drug abemaciclib in combination with nonsteroidal aromatase inhibitors (anastrozole or letrozole) is effective in participants with Hormone Receptor Positive (HR+), Human Epidermal Growth Factor Receptor 2 Negative (HER2-) advanced breast cancer that have certain disease characteristics.
Study identification
- NCT ID
- NCT03988114
- Recruitment status
- Withdrawn
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- Not listed
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 16, 2019 (Estimated)
- Primary completion
- Mar 23, 2022 (Estimated)
- Completion
- Mar 23, 2023 (Estimated)
- Last update posted
- Sep 6, 2019
2019 – 2023
United States locations
- U.S. sites
- 70
- U.S. states
- 21
- U.S. cities
- 63
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern Cancer Center, P.C. | Daphne | Alabama | 36526 | — |
| Arizona Oncology Associates, P.C. | Tempe | Arizona | 85284 | — |
| Compassionate Cancer Care Medical Group Inc | Fountain Valley | California | 92708 | — |
| California Cancer Associates Research and Excellence (cCARE) | Fresno | California | 93720 | — |
| Beaver Medical Group | Highland | California | 92346 | — |
| Pacific Cancer Care | Monterey | California | 93940 | — |
| St. Joseph Hospital | Orange | California | 92868 | — |
| Comprehensive Cancer Centers of the Desert | Palm Springs | California | 92262 | — |
| California Cancer Associates in Research and Excellence | San Marcos | California | 92069 | — |
| Cancer Center of Santa Barbara with Sansum Clinic | Santa Barbara | California | 93105 | — |
| UCLA Medical Center | Torrance | California | 90502 | — |
| Memorial Hospital | Colorado Springs | Colorado | 80909 | — |
| Rocky Mountain Cancer Center | Lone Tree | Colorado | 80124 | — |
| Medical Oncology Hematology Consultants, PA | Newark | Delaware | 19713 | — |
| BayCare Medical Group | Clearwater | Florida | 33756 | — |
| Florida Cancer Specialists | Fort Myers | Florida | 33901 | — |
| Woodlands Medical Specialists | Pensacola | Florida | 32503 | — |
| Cancer Specialists of North Florida -St Augustine | Saint Augustine | Florida | 32086 | — |
| Florida Cancer Specialists | St. Petersburg | Florida | 33705 | — |
| Florida Cancer Specialists | Tallahassee | Florida | 32308 | — |
| Florida Cancer Specialists | West Palm Beach | Florida | 33401 | — |
| Cleveland Clinic of Florida | Weston | Florida | 33331 | — |
| Summit Cancer Care | Savannah | Georgia | 31404 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Illinois Cancer Specialists-Niles | Niles | Illinois | 60714 | — |
| Community Health Network | Indianapolis | Indiana | 46219 | — |
| Central Maine Medical Center | Lewiston | Maine | 04240 | — |
| York Hospital | York Village | Maine | 03909 | — |
| HCA Midwest | Kansas City | Missouri | 64132 | — |
| Oncology Hematology West | Omaha | Nebraska | 68130 | — |
| Comprehensive Cancer Centers of Nevada | Henderson | Nevada | 89052 | — |
| Valley Health System | Paramus | New Jersey | 07652 | — |
| Broome Oncology LLC | Johnson City | New York | 13790 | — |
| Abington Hematology Oncology Associates | Horsham | Pennsylvania | 19044 | — |
| Charleston Hematology Oncology Associates | Charleston | South Carolina | 29414 | — |
| Sarah Cannon Research Institute SCRI | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology PLLC | Nashville | Tennessee | 37203 | — |
| Texas Oncology - Abilene | Abilene | Texas | 79606 | — |
| Texas Oncology - Amarillo | Amarillo | Texas | 79106 | — |
| Texas Oncology-Arlington South | Arlington | Texas | 76014 | — |
| Texas Oncology Cancer Center | Austin | Texas | 78731 | — |
| Texas Oncology - Bedford | Bedford | Texas | 76022 | — |
| Texas Oncology P.A. | Dallas | Texas | 75203 | — |
| Texas Oncology - Medical City Dallas | Dallas | Texas | 75230 | — |
| Texas Oncology - Dallas Presbyterian Hospital | Dallas | Texas | 75231 | — |
| Texas Oncology-Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | — |
| Texas Oncology - Marnie McFadden Ward Cancer Center | Dallas | Texas | 77702 | — |
| Texas Oncology P.A. | El Paso | Texas | 79902 | — |
| Texas Oncology Flower Mound | Flower Mound | Texas | 75028 | — |
| The Center for Cancer and Blood Disorders | Fort Worth | Texas | 76104 | — |
| Texas Oncology-Memorial City | Houston | Texas | 77024 | — |
| Renovatio Clinical | Houston | Texas | 77056 | — |
| Texas Oncology - McAllen | McAllen | Texas | 78503 | — |
| Texas Oncology-McKinney | McKinney | Texas | 75771 | — |
| Texas Oncology- Mesquite | Mesquite | Texas | 75150 | — |
| Texas Oncology - Midland Allison Cancer Center | Midland | Texas | 79701 | — |
| Texas Oncology - Paris | Paris | Texas | 75460 | — |
| Texas Oncology-Plano East | Plano | Texas | 75075 | — |
| Texas Oncology-Plano West | Plano | Texas | 75093 | — |
| Texas Oncology - San Antonio Medical Center | San Antonio | Texas | 78217 | — |
| Texas Oncology-Sherman | Sherman | Texas | 75090-0504 | — |
| US Oncology | The Woodlands | Texas | 77380 | — |
| Tyler Cancer Center | Tyler | Texas | 75702 | — |
| Texas Oncology-Deke Slayton Cancer Center | Webster | Texas | 77598-4219 | — |
| Texas Oncology-Wichital Falls Texoma Cancer Center | Wichita Falls | Texas | 76310 | — |
| Intermountain Medical Center | St. George | Utah | 84790 | — |
| Hematology Oncology Associates of Fredericksburg Inc. | Fredericksburg | Virginia | 22408 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Oncology and Hematology Associates of Southwest Virginia Inc | Salem | Virginia | 24153 | — |
| Shenandoah Oncology, P.C. | Winchester | Virginia | 22601 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 49 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03988114, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 6, 2019 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03988114 live on ClinicalTrials.gov.