ClinicalTrials.gov record
Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD
ClinicalTrials.gov ID: NCT04023552
Public ClinicalTrials.gov record NCT04023552. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Double-blind, Placebo-controlled, Multicenter Trial Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With Established Cardiovascular Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a pivotal phase 3 study designed to support an indication for the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a)
Study identification
- NCT ID
- NCT04023552
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 8,323 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 12, 2019 (Actual)
- Primary completion
- Jul 16, 2026 (Actual)
- Completion
- Jul 16, 2026 (Actual)
- Last update posted
- Aug 28, 2026
2019 – 2026
United States locations
- U.S. sites
- 287
- U.S. states
- 38
- U.S. cities
- 139
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| SEC Clinical Research LLC | Andalusia | Alabama | 36420 | — |
| Grandview Med Group Research LLC | Birmingham | Alabama | 35243 | — |
| Novartis Investigative Site | Birmingham | Alabama | 35243 | — |
| Heart Center Research Llc | Huntsville | Alabama | 35801 | — |
| Novartis Investigative Site | Huntsville | Alabama | 35801 | — |
| Mobile Heart Specialists | Mobile | Alabama | 36608 | — |
| Novartis Investigative Site | Mobile | Alabama | 36608 | — |
| Novartis Investigative Site | Cottonwood | Arizona | 86326 | — |
| Mercy Gilbert Medical Center | Gilbert | Arizona | 85297 | — |
| Clinical Research Inst of Arizona | Sun City West | Arizona | 85375 | — |
| Novartis Investigative Site | Sun City West | Arizona | 85375 | — |
| Eclipse Clinical Research | Tucson | Arizona | 85745 | — |
| Novartis Investigative Site | Tucson | Arizona | 85745 | — |
| Cardiology and Medicine Clinic PA | Little Rock | Arkansas | 72204 | — |
| Novartis Investigative Site | Little Rock | Arkansas | 72204 | — |
| Cardiovascular Res Found | Beverly Hills | California | 90210 | — |
| National Heart Institute | Beverly Hills | California | 90211 | — |
| Novartis Investigative Site | Beverly Hills | California | 90211 | — |
| Flourish Clinical Resrch Covin | Covina | California | 91723 | — |
| Novartis Investigative Site | Covina | California | 91723 | — |
| Diabetes Lipid Management Center | Huntington Beach | California | 92648 | — |
| Novartis Investigative Site | Huntington Beach | California | 92648 | — |
| University of Calif Irvine Med Cntr | Irvine | California | 92660 | — |
| Novartis Investigative Site | La Jolla | California | 92037 | — |
| Memorial Care Health System | Long Beach | California | 90806 | — |
| Novartis Investigative Site | Long Beach | California | 90806 | — |
| Keck Medical Center USC | Los Angeles | California | 90033 | — |
| Novartis Investigative Site | Los Angeles | California | 90033 | — |
| Novartis Investigative Site | Los Angeles | California | 90073 | — |
| Novartis Investigative Site | Northridge | California | 91325 | — |
| Valley Clinical Trials | Northridge | California | 91325 | — |
| Novartis Investigative Site | Orange | California | 92868 | — |
| Stanford University Medical Center | Palo Alto | California | 94304 | — |
| University of California San Diego | San Diego | California | 92103 | — |
| UCSF | San Francisco | California | 94115 | — |
| Novartis Investigative Site | San Francisco | California | 94158 | — |
| Helping Hands Medical Associates INC | Santa Ana | California | 92704 | — |
| Novartis Investigative Site | Santa Ana | California | 92704 | — |
| Novartis Investigative Site | Stanford | California | 94305 | — |
| Manshadi Heart Institute | Stockton | California | 95204 | — |
| Novartis Investigative Site | Stockton | California | 95204 | — |
| Interv Cardiology Med Grp | West Hills | California | 91307 | — |
| Novartis Investigative Site | West Hills | California | 91307 | — |
| Novartis Investigative Site | Aurora | Colorado | 80045 | — |
| Univ Of Color Anschutz Med Center | Aurora | Colorado | 80045 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| Novartis Investigative Site | Bridgeport | Connecticut | 06610 | — |
| Novartis Investigative Site | Hartford | Connecticut | 06102-5037 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Chase Medical Research LLC | Waterbury | Connecticut | 06708 | — |
| Novartis Investigative Site | Waterbury | Connecticut | 06708 | — |
| Excel Medical Clinical Trials LLC | Boca Raton | Florida | 33434 | — |
| Novartis Investigative Site | Boca Raton | Florida | 33434 | — |
| Cardiovascular and Vein Center of Florida | Bradenton | Florida | 34209 | — |
| Novartis Investigative Site | Bradenton | Florida | 34209 | — |
| Bay Area Cardiology Assoc | Brandon | Florida | 33511 | — |
| Novartis Investigative Site | Brandon | Florida | 33511 | — |
| Novartis Investigative Site | Fort Lauderdale | Florida | 33312 | — |
| CV Consultants of South Broward | Hollywood | Florida | 33021 | — |
| Novartis Investigative Site | Jacksonville | Florida | 32205 | — |
| Westside Center for Clinical Research | Jacksonville | Florida | 32205 | — |
| East Coast Institute for Research | Jacksonville | Florida | 32216 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Novartis Investigative Site | Jacksonville | Florida | 32216 | — |
| Infinite Clinical Research | Miami | Florida | 33133 | — |
| Novartis Investigative Site | Miami | Florida | 33133 | — |
| Advanced Research for Health Improvement LLC | Naples | Florida | 34102 | — |
| Novartis Investigative Site | Naples | Florida | 34102 | — |
| Southwest Florida Research | Naples | Florida | 34102 | — |
| Novartis Investigative Site | Port Charlotte | Florida | 33952 | — |
| Peace River Cardiovascular Center | Port Charlotte | Florida | 33952 | — |
| Novartis Investigative Site | Port Orange | Florida | 32127 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| East Coast Inst for Research LLC | Saint Augustine | Florida | 32086 | — |
| Novartis Investigative Site | Saint Augustine | Florida | 32086 | — |
| Cardiology Partners Clinical Research Institute | Wellington | Florida | 33449 | — |
| Novartis Investigative Site | Wellington | Florida | 33449 | — |
| Novartis Investigative Site | Atlanta | Georgia | 30084 | — |
| Grady Health System | Atlanta | Georgia | 30303 | — |
| Novartis Investigative Site | Atlanta | Georgia | 30309 | — |
| Piedmont Heart Institute | Atlanta | Georgia | 30309 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Novartis Investigative Site | Atlanta | Georgia | 30324 | — |
| Novartis Investigative Site | Dunwoody | Georgia | 30338 | — |
| Alta Pharmaceutical Research Center | Peachtree Corners | Georgia | 30092 | — |
| Cardiovascular Consultants of S GA | Thomasville | Georgia | 31792 | — |
| Novartis Investigative Site | Thomasville | Georgia | 31792 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Advocate Lutheran General Childrens Hospital | Park Ridge | Illinois | 60068 | — |
| Novartis Investigative Site | Park Ridge | Illinois | 60068 | — |
| Novartis Investigative Site | Indianapolis | Indiana | 46202 4800 | — |
| Krannert Institute of Cardiology | Indianapolis | Indiana | 46202-4800 | — |
| Novartis Investigative Site | Iowa City | Iowa | 52242 | — |
| Uni Of Iowa Hospitals And Clinics | Iowa City | Iowa | 52242 | — |
| Novartis Investigative Site | Kansas City | Kansas | 66160 | — |
| University of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| Cotton O Neil Clinical Res Center | Topeka | Kansas | 66606 | — |
| Novartis Investigative Site | Topeka | Kansas | 66606 | — |
| Christus Health Central Louisiana | Alexandria | Louisiana | 71301 | — |
| Novartis Investigative Site | Alexandria | Louisiana | 71301 | — |
| Novartis Investigative Site | Baton Rouge | Louisiana | 70808 | — |
| Novartis Investigative Site | Bogalusa | Louisiana | 70427 | — |
| Novartis Investigative Site | Bossier City | Louisiana | 71111 | — |
| Cardiovascular Associates Research | Covington | Louisiana | 70433 | — |
| Louisiana Heart Center Research | Covington | Louisiana | 70433 | — |
| Novartis Investigative Site | Covington | Louisiana | 70433 | — |
| Novartis Investigative Site | Eunice | Louisiana | 70535 | — |
| Heart Clinic of Hammond | Hammond | Louisiana | 70403 | — |
| Novartis Investigative Site | Hammond | Louisiana | 70403 | — |
| CV Institute of the South | Houma | Louisiana | 70360 | — |
| Novartis Investigative Site | Houma | Louisiana | 70360 | — |
| Horizon Research Grp | Lafayette | Louisiana | 70501 | — |
| Novartis Investigative Site | Metairie | Louisiana | 70006 | — |
| Omega Clinical Research | Metairie | Louisiana | 70006 | — |
| Tulane Uni Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Crescent City Physicians Inc | New Orleans | Louisiana | 70115 | — |
| Novartis Investigative Site | New Orleans | Louisiana | 70115 | — |
| CV Ins of the South | Opelousas | Louisiana | 70570 | — |
| Novartis Investigative Site | Opelousas | Louisiana | 70570 | — |
| Grace Research Llc | Shreveport | Louisiana | 71105 | — |
| Novartis Investigative Site | Shreveport | Louisiana | 71105 | — |
| Louisiana Heart Center Research | Slidell | Louisiana | 70458 | — |
| Novartis Investigative Site | Slidell | Louisiana | 70458 | — |
| Southern Clinical Research | Zachary | Louisiana | 70791 | — |
| Maine Health Cardiology | Scarborough | Maine | 04074 | — |
| Novartis Investigative Site | Scarborough | Maine | 04074 | — |
| Novartis Investigative Site | Baltimore | Maryland | 21201 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Novartis Investigative Site | Baltimore | Maryland | 21209 | — |
| Sinai Ct for Throm Res and Drug Dev | Baltimore | Maryland | 21209 | — |
| Johns Hopkins Univ School of Med | Baltimore | Maryland | 21287 | — |
| Novartis Investigative Site | Baltimore | Maryland | 21287 | — |
| Johns Hopkins University | Columbia | Maryland | 21044 | — |
| Novartis Investigative Site | Columbia | Maryland | 21044 | — |
| Anderson Medical Research | Ft. Washington | Maryland | 20744 | — |
| Novartis Investigative Site | Ft. Washington | Maryland | 20744 | — |
| Adventist HealthCare Shady Grove Medical Center | Rockville | Maryland | 20850 | — |
| Novartis Investigative Site | Rockville | Maryland | 20850 | — |
| MGH | Boston | Massachusetts | 02114-2696 | — |
| Novartis Investigative Site | Boston | Massachusetts | 02114-2696 | — |
| Brigham and Womens Hosp Harvard Med School | Boston | Massachusetts | 02115 | — |
| Novartis Investigative Site | Boston | Massachusetts | 02115 | — |
| Novartis Investigative Site | Detroit | Michigan | 48201 | — |
| Wayne State University | Detroit | Michigan | 48201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Novartis Investigative Site | Detroit | Michigan | 48202 | — |
| AA Medical Research Center | Flint | Michigan | 48504 | — |
| Novartis Investigative Site | Flint | Michigan | 48504 | — |
| Genesys Regional Medical Center | Grand Blanc | Michigan | 48439 | — |
| Novartis Investigative Site | Grand Blanc | Michigan | 48439 | — |
| Novartis Investigative Site | Kalamazoo | Michigan | 49008 | — |
| Western Michigan University | Kalamazoo | Michigan | 49008 | — |
| McLaren Ctr Research Innovation | Petoskey | Michigan | 49770 | — |
| Novartis Investigative Site | Petoskey | Michigan | 49770 | — |
| Central Michigan University | Saginaw | Michigan | 48601 | — |
| Novartis Investigative Site | Saginaw | Michigan | 48601 | — |
| Metro Health Univ of MI Health | Wyoming | Michigan | 49519 | — |
| Novartis Investigative Site | Wyoming | Michigan | 49519 | — |
| Saint Johns Hospital | Maplewood | Minnesota | 55109 | — |
| Minneapolis Heart Institute | Minneapolis | Minnesota | 55407 | — |
| Novartis Investigative Site | Minneapolis | Minnesota | 55407 | — |
| Novartis Investigative Site | Minneapolis | Minnesota | 55455 | — |
| University Of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Belzoni Clinical Research | Belzoni | Mississippi | 39038 | — |
| Novartis Investigative Site | Belzoni | Mississippi | 39038 | — |
| Novartis Investigative Site | Southaven | Mississippi | 38671 | — |
| Stern Cardiovascular Foundation Inc | Southaven | Mississippi | 38671 | — |
| Novartis Investigative Site | City of Saint Peters | Missouri | 63303 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Novartis Investigative Site | St Louis | Missouri | 63110 | — |
| Washington Univ School Of Medicine | St Louis | Missouri | 63110 | — |
| Mercy South | St Louis | Missouri | 63128 | — |
| Mercy Hospital St Louis | St Louis | Missouri | 63141 | — |
| Novartis Investigative Site | Lincoln | Nebraska | 68526 | — |
| Novartis Investigative Site | Omaha | Nebraska | 68114 | — |
| Quality Clinical Research | Omaha | Nebraska | 68114 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Novartis Investigative Site | Lebanon | New Hampshire | 03756 | — |
| Novartis Investigative Site | Ridgewood | New Jersey | 07450 | — |
| The Valley Hospital | Ridgewood | New Jersey | 07450 | — |
| Novartis Investigative Site | Summit | New Jersey | 07901 | — |
| Overlook Medical Center | Summit | New Jersey | 07901 | — |
| Albany Medical College | Albany | New York | 12206 | — |
| Northwell Health | Manhasset | New York | 11030 | — |
| Novartis Investigative Site | Manhasset | New York | 11030 | — |
| New York Uni Med Ctr | New York | New York | 10016 | — |
| Novartis Investigative Site | New York | New York | 10016 | — |
| Novartis Investigative Site | New York | New York | 10021 | — |
| Weill Cornell Medical Center | New York | New York | 10021 | — |
| Icahn School of Med at Mt Sinai | New York | New York | 10029 | — |
| Novartis Investigative Site | New York | New York | 10029 | — |
| Novartis Investigative Site | New York | New York | 10075 | — |
| Lenox Hill Hospital | New York | New York | 43210 | — |
| Northwell Health Physician Peconic | Riverhead | New York | 11901 | — |
| Rochester Regional Health | Rochester | New York | 14621 | — |
| Strong Memorial Hospital | Rochester | New York | 14642 | — |
| Novartis Investigative Site | Southampton | New York | 11968 | — |
| Novant Health Heart Vas Inst | Charlotte | North Carolina | 28204 | — |
| Novartis Investigative Site | Charlotte | North Carolina | 28204 | — |
| Medication Management LLC | Greensboro | North Carolina | 27405 | — |
| Novartis Investigative Site | Greensboro | North Carolina | 27405 | — |
| Novartis Investigative Site | High Point | North Carolina | 27262 | — |
| Accellacare US Inc | Raleigh | North Carolina | 27609 | — |
| Novartis Investigative Site | Sanford | North Carolina | 27330 | — |
| Jones Family Practice PA | Shelby | North Carolina | 28150 | — |
| Novartis Investigative Site | Shelby | North Carolina | 28150 | — |
| Novartis Investigative Site | Winston-Salem | North Carolina | 27157 | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Novartis Investigative Site | Akron | Ohio | 44304 | — |
| Akron Hospital Summa Health System | Akron | Ohio | 44309 | — |
| Aultman Hospital | Canton | Ohio | 44710 | — |
| Novartis Investigative Site | Canton | Ohio | 44710 | — |
| Lindner Ctr At The Christ Hosp | Cincinnati | Ohio | 45219 | — |
| Novartis Investigative Site | Cincinnati | Ohio | 45219 | — |
| Novartis Investigative Site | Cincinnati | Ohio | 45246 | — |
| Velocity Clin Research Springdale | Cincinnati | Ohio | 45246 | — |
| Novartis Investigative Site | Cincinnati | Ohio | 45267 | — |
| University Of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Novartis Investigative Site | Cleveland | Ohio | 44195 | — |
| Novartis Investigative Site | Columbus | Ohio | 43210 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Novartis Investigative Site | Marion | Ohio | 43302 | — |
| Rama Research LLC | Marion | Ohio | 43302 | — |
| Novartis Investigative Site | Portland | Oregon | 97239 | — |
| Oregon Health Sciences University | Portland | Oregon | 97239 | — |
| Lancaster General Health | Lancaster | Pennsylvania | 17603 | — |
| Novartis Investigative Site | Lancaster | Pennsylvania | 17603 | — |
| Novartis Investigative Site | Philadelphia | Pennsylvania | 19104 | — |
| Perelman School of Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Cardiology Consultants of Philadelphia | Yardley | Pennsylvania | 19067 | — |
| Novartis Investigative Site | Yardley | Pennsylvania | 19067 | — |
| Miriam Hospital | Providence | Rhode Island | 02906 | — |
| Novartis Investigative Site | Providence | Rhode Island | 02906 | — |
| Novartis Investigative Site | Fort Mill | South Carolina | 29707 | — |
| Piedmont Research Partners LLC | Fort Mill | South Carolina | 29707 | — |
| Novartis Investigative Site | Summerville | South Carolina | 29485 | — |
| Palmetto Clinical Research | Summerville | South Carolina | 29485 | — |
| Monument Health Clinical Research | Rapid City | South Dakota | 57701 | — |
| Novartis Investigative Site | Rapid City | South Dakota | 57701 | — |
| Novartis Investigative Site | Germantown | Tennessee | 38138 | — |
| The Stern Cardiovascular Foundation | Germantown | Tennessee | 38138 | — |
| Apex Cardiology Research Associates of Jackson | Jackson | Tennessee | 38301 | — |
| Novartis Investigative Site | Jackson | Tennessee | 38301 | — |
| Novartis Investigative Site | Nashville | Tennessee | 37232 | — |
| Vanderbilt Univ Medi Cen | Nashville | Tennessee | 37232 | — |
| Cardiovascular Res of Knoxville LLC | Powell | Tennessee | 37849 | — |
| Novartis Investigative Site | Powell | Tennessee | 37849 | — |
| Novartis Investigative Site | Dallas | Texas | 75226 | — |
| Soltero Cardiovascular Research Center | Dallas | Texas | 75226 | — |
| North Texas Endocrine Center | Dallas | Texas | 75231 | — |
| Novartis Investigative Site | Dallas | Texas | 75231 | — |
| Novartis Investigative Site | Dallas | Texas | 75235 | — |
| SW Family Medicine Associates | Dallas | Texas | 75235 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Baylor College Of Medicine | Houston | Texas | 77030 | — |
| Novartis Investigative Site | Houston | Texas | 77030 | — |
| Novartis Investigative Site | Livingston | Texas | 77351 | — |
| Grace Research | Marshall | Texas | 75670 | — |
| Novartis Investigative Site | Temple | Texas | 76508 | — |
| Northwest Houston Clinical Research PLLC | Tomball | Texas | 77375 | — |
| Novartis Investigative Site | Tomball | Texas | 77375 | — |
| Novartis Investigative Site | Bountiful | Utah | 84010 | — |
| Progressive Clinical Research | Bountiful | Utah | 84010 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| Novartis Investigative Site | Murray | Utah | 84107 | — |
| The University of Utah | Salt Lake City | Utah | 84132-0001 | — |
| Novartis Investigative Site | Danville | Virginia | 24541 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | — |
| Novartis Investigative Site | Falls Church | Virginia | 22042 | — |
| Virginia Heart | Falls Church | Virginia | 22042 | — |
| Carient Heart and Vascular | Manassas | Virginia | 20109 | — |
| Novartis Investigative Site | Manassas | Virginia | 20109 | — |
| York Clinical Research | Norfolk | Virginia | 23504 | — |
| Novartis Investigative Site | Norfolk | Virginia | 23510 | — |
| Dominion Medical Associates | Richmond | Virginia | 23219 | — |
| Novartis Investigative Site | Richmond | Virginia | 23219 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| Novartis Investigative Site | Seattle | Washington | 98104 | — |
| Novartis Investigative Site | Seattle | Washington | 98122 | — |
| Swedish Medical Center-Cardiovascular Research | Seattle | Washington | 98122 | — |
| Novartis Investigative Site | Seattle | Washington | 98195 | — |
| Univ of Washington Medical Center | Seattle | Washington | 98195 | — |
| West Virginia University Hospital | Morgantown | West Virginia | 26506 | — |
| Novartis Investigative Site | Milwaukee | Wisconsin | 53215 | — |
| St Luke s Medical Center Aurora | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 615 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04023552, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 28, 2026 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04023552 live on ClinicalTrials.gov.