Encorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer
Public ClinicalTrials.gov record NCT04044430. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase I/II Trial of Encorafenib, Binimetinib, and Nivolumab in Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer
Study identification
- NCT ID
- NCT04044430
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- University of California, San Francisco
- Other
- Enrollment
- 2 participants
Conditions and interventions
Conditions
- Metastatic Colon Adenocarcinoma
- Metastatic Colorectal Adenocarcinoma
- Metastatic Microsatellite Stable Colorectal Carcinoma
- Metastatic Rectal Adenocarcinoma
- Stage III Colon Cancer
- Stage III Colorectal Cancer
- Stage III Rectal Cancer
- Stage IIIA Colon Cancer
- Stage IIIA Colorectal Cancer
- Stage IIIA Rectal Cancer
- Stage IIIB Colon Cancer
- Stage IIIB Colorectal Cancer
- Stage IIIB Rectal Cancer
- Stage IIIC Colon Cancer
- Stage IIIC Colorectal Cancer
- Stage IIIC Rectal Cancer
- Stage IV Colon Cancer
- Stage IV Colorectal Cancer
- Stage IV Rectal Cancer
- Stage IVA Colon Cancer
- Stage IVA Colorectal Cancer
- Stage IVA Rectal Cancer
- Stage IVB Colon Cancer
- Stage IVB Colorectal Cancer
- Stage IVB Rectal Cancer
- Stage IVC Colon Cancer
- Stage IVC Colorectal Cancer
- Stage IVC Rectal Cancer
Interventions
- Binimetinib Drug
- Encorafenib Drug
- Nivolumab Biological
- Questionnaire Administration Other
Drug · Biological · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 30, 2020
- Primary completion
- Jul 30, 2022
- Completion
- Jul 30, 2022
- Last update posted
- Jan 8, 2023
2020 – 2022
United States locations
- U.S. sites
- 2
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kaiser Permanente Northern California | San Francisco | California | 94115 | — |
| Univeristy of California, San Francisco | San Francisco | California | 94115 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04044430, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 8, 2023 · Synced May 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04044430 live on ClinicalTrials.gov.