GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors
Public ClinicalTrials.gov record NCT04083599. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A First-in-Human, Open-label, Dose-escalation Trial With Expansion Cohorts to Evaluate Safety and Anti-tumor Activity of GEN1042 in Subjects With Malignant Solid Tumors
Study identification
- NCT ID
- NCT04083599
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Genmab
- Industry
- Enrollment
- 350 participants
Conditions and interventions
Conditions
Interventions
- 5-FU Drug
- Carboplatin Drug
- Cisplatin Drug
- GEN1042 Biological
- Gemcitabine Drug
- Nab paclitaxel Drug
- Paclitaxel Drug
- Pembrolizumab Drug
- Pemetrexed Drug
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 16, 2019
- Primary completion
- Dec 29, 2025
- Completion
- Oct 31, 2026
- Last update posted
- May 5, 2026
2019 – 2026
United States locations
- U.S. sites
- 23
- U.S. states
- 17
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alaska Oncology and Hematology LLC | Anchorage | Alaska | 99508 | — |
| Cancer & Blood Specialty Clinic | Los Alamitos | California | 90720 | — |
| Moores Cancer Center at the UC San Diego Health | San Diego | California | 92037 | — |
| Yale University Cancer Center | New Haven | Connecticut | 06520 | — |
| ChristianaCare | Newark | Delaware | 19713 | — |
| Mount Sinai Comprehensive Cancer Center | Miami Beach | Florida | 33140 | — |
| Florida Cancer Affiliates | Ocala | Florida | 34474 | — |
| Hope and Healing Cancer Services | Hinsdale | Illinois | 60521 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | — |
| Maryland Oncology Hematology PA | Columbia | Maryland | 21044 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Levine Cancer Center | Charlotte | North Carolina | 28204 | — |
| Novant Health Cancer Institute - Forsyth (Medical Oncology) | Winston-Salem | North Carolina | 27103 | — |
| Kaiser Permanente (KP) Oncology/Hematology | Portland | Oregon | 97227 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| Lumi Research | Kingwood | Texas | 77339 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84124 | — |
| Virgina Cancer Specialists | Fairfax | Virginia | 22031 | — |
| Adventist Health System/Sunbelt,Inc | Seattle | Washington | 98109 | — |
| Medical Oncology Associates, PS | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 53 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04083599, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04083599 live on ClinicalTrials.gov.