ClinicalTrials.gov record
Completed Phase 1 Interventional

Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

ClinicalTrials.gov ID: NCT04084951

Public ClinicalTrials.gov record NCT04084951. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 2:30 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Multicenter, Open-Label, Dose Escalation and Dose Expansion Study of SQZ-PBMC-HPV as Monotherapy and in Combination With Atezolizumab or Other Immune Checkpoint Inhibitors in HLA-A*02+ Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

Study identification

NCT ID
NCT04084951
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
SQZ Biotechnologies
Industry
Enrollment
30 participants

Conditions and interventions

Interventions

  • Atezolizumab Drug
  • Ipilimumab Drug
  • Nivolumab Drug
  • SQZ-PBMC-HPV Biological

Drug · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 27, 2020
Primary completion
Feb 8, 2023
Completion
Feb 8, 2023
Last update posted
Apr 13, 2023

2020 – 2023

United States locations

U.S. sites
10
U.S. states
10
U.S. cities
10
Facility City State ZIP Site status
HonorHealth Scottsdale Arizona 85258
Cedars-Sinai Medical Center Los Angeles California 90048
University of Colorado Anschutz Cancer Pavillion Aurora Colorado 80045
University of Kansas Cancer Center Kansas City Kansas 66160
Massachusetts General Hospital Boston Massachusetts 02114
The Masonic Cancer Center University of Minnesota Minneapolis Minnesota 55455
University of Nebraska Medical Center Omaha Nebraska 68198-6840
OU Health Stephenson Cancer Center Oklahoma City Oklahoma 73104
Providence Cancer Institute Portland Oregon 97213
Vanderbilt University Medical Center Nashville Tennessee 37212

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04084951, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 13, 2023 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04084951 live on ClinicalTrials.gov.

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