Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia
Public ClinicalTrials.gov record NCT04119050. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia: A Multicenter, Randomized, Double-blind, Placebo-controlled Study With a Long-term Open-label Extension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to evaluate the efficacy and safety of M281 in participants with warm autoimmune hemolytic anemia (wAIHA).
Study identification
- NCT ID
- NCT04119050
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 118 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 15, 2019 (Actual)
- Primary completion
- Feb 2, 2025 (Actual)
- Completion
- Apr 1, 2028 (Estimated)
- Last update posted
- Aug 31, 2026
2019 – 2028
United States locations
- U.S. sites
- 29
- U.S. states
- 15
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MemorialCare Medical Group | Fountain Valley | California | 92708 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| Compassionate Cancer Care | Riverside | California | 92501 | — |
| American Institute of Research | Whittier | California | 90603 | — |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| GNP Research | Cooper City | Florida | 33024 | — |
| University of Florida College of Medicine | Gainesville | Florida | 32610 | — |
| 21st Century Oncology | Jacksonville | Florida | 32204 | — |
| Lakes Research | Miami Lakes | Florida | 33014 | — |
| AdventHealth Cancer Institute | Orlando | Florida | 32804 | — |
| Children's Research Institute | St. Petersburg | Florida | 33701 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Alliance for Multispeciality Research | Merriam | Kansas | 66204 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| Henry Ford Medical Center | Detroit | Michigan | 48202 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Montefiore Medical Center | Lake Success | New York | 11042 | — |
| Monter Cancer Center | Lake Success | New York | 11042 | — |
| Hematology Oncology Associates of Rockland | Nyack | New York | 10960 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| East Carolina University | Greenville | North Carolina | 27834 | — |
| Taussig Cancer Insititute Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University- James Cancer Hospital | Columbus | Ohio | 43210 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| West Penn Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| Northwest Medical Specialists | Tacoma | Washington | 98405 | — |
| University of Wisconsin Carbone Cancer Center | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 142 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04119050, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 31, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04119050 live on ClinicalTrials.gov.