A Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC
Public ClinicalTrials.gov record NCT04155190. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double Blind, Vehicle-controlled, Phase 2 Efficacy and Safety Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Patients With Non-Gorlin High Frequency BCC
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, randomized, double-blind, stratified, vehicle-controlled study of the efficacy and safety of Patidegib Topical Gel, 2%, applied topically twice daily to the face of adult participants with non-Gorlin HF-BCC (high-frequency basal cell carcinoma). Participants will be randomized (1:1) to receive either Patidegib Topical Gel, 2%, or Vehicle for 9 months. Randomization will be stratified by gender. The primary endpoint is the number of nSEB (surgically eligible basal cell carcinoma) that develop on the face over the 9 month period. The primary end point will be assessed by imaging and tracking of BCCs consistently throughout the study in order to identify nSEBs.
Study identification
- NCT ID
- NCT04155190
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 50 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 20, 2019 (Actual)
- Primary completion
- Apr 23, 2021 (Actual)
- Completion
- Apr 23, 2021 (Actual)
- Last update posted
- Jul 21, 2026
2019 – 2021
United States locations
- U.S. sites
- 14
- U.S. states
- 8
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Axiom Research, LLC | Apple Valley | California | 92307 | — |
| Axiom Research, LLC | Colton | California | 92324 | — |
| Center for Dermatology Clinical Research, Inc. | Fremont | California | 94538 | — |
| Dermatology Research Associates | Los Angeles | California | 90045 | — |
| The Dermatology Center of Newport | Newport Beach | California | 92660 | — |
| Palm Beach Dermatology Research | Delray Beach | Florida | 33484 | — |
| Leavitt Medical Associates of Florida | Ormond Beach | Florida | 32174 | — |
| PellePharm Investigative Site | Saint Augustine | Florida | 32080 | — |
| The Indiana Clinical Trials Center | Plainfield | Indiana | 46168 | — |
| Grekin Skin Institute | Warren | Michigan | 48088 | — |
| PellePharm Investigative Site | Henderson | Nevada | 89052 | — |
| Skin Laser and Surgery Specialists of NY&NJ | Hackensack | New Jersey | 07601 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| University of Utah | Murray | Utah | 84107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04155190, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 21, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04155190 live on ClinicalTrials.gov.