Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer
Public ClinicalTrials.gov record NCT04163900. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Open-Label, Multi-Centre, Randomized Study Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Previously Untreated Locally Advanced or Metastatic Biliary Tract Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
NuTide:121 compares NUC-1031 with gemcitabine, both in combination with cisplatin, in patients with previously untreated advanced biliary tract cancer. The primary hypotheses are: * The combination of NUC-1031 plus cisplatin prolongs overall survival compared to the gemcitabine plus cisplatin standard of care * The combination of NUC-1031 plus cisplatin increases overall response rate compared to the gemcitabine plus cisplatin standard of care
Study identification
- NCT ID
- NCT04163900
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 773 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 24, 2019 (Actual)
- Primary completion
- Mar 2, 2022 (Actual)
- Completion
- Apr 5, 2022 (Actual)
- Last update posted
- May 24, 2023
2019 – 2022
United States locations
- U.S. sites
- 29
- U.S. states
- 19
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Oncology Associates , PC - HOPE | Tucson | Arizona | 85711 | — |
| University of Arizona Cancer Center | Tucson | Arizona | 85719 | — |
| The Oncology Institute of Hope and Innovation | Whittier | California | 90602-3171 | — |
| Rocky Mountain Cancer Centers, LLP- Aurora | Aurora | Colorado | 80012 | — |
| Baptist Health Medical Group Oncology, LLC | Miami | Florida | 33176 | — |
| Orlando Health, Inc. | Orlando | Florida | 32806 | — |
| IACT Health | Columbus | Georgia | 31904 | — |
| Affiliated Oncologists LLC | Chicago Ridge | Illinois | 60415 | — |
| University of Kansas Medical Center Research Institute, Inc. | Westwood | Kansas | 66205 | — |
| Norton Cancer Institute | Louisville | Kentucky | 40217 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215-5400 | — |
| Henry Ford Medical Group | Detroit | Michigan | 48202 | — |
| Minnesota Oncology Hemtology | Minneapolis | Minnesota | 55404 | — |
| Regents of the University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| University of Rochester Medical Center - Strong Memorial Hospital | Rochester | New York | 14642 | — |
| The Research Foundation for The State University of New York | Stony Brook | New York | 11794-3369 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| The Ohio State University James Cancer Hospital and Solove Research Institute | Columbus | Ohio | 43210 | — |
| Corporal Michael J. Crescenz VA Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Prisma Health Upstate | Greenville | South Carolina | 29605 | — |
| Texas Oncology, P.A. - Austin | Austin | Texas | 78705 | — |
| Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410 | — |
| Texas Oncology, P.A. - Tyler | Tyler | Texas | 75702 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| Northwest Cancer Specialists, P.C.-Vancouver | Vancouver | Washington | 98684 | — |
| Wenatchee Valley Hospital and Clinics | Wenatchee | Washington | 98801 | — |
| The Medical College of Wisconsin, Inc. | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 96 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04163900, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 24, 2023 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04163900 live on ClinicalTrials.gov.