A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM)
Public ClinicalTrials.gov record NCT04173494. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Phase 3 Study to Evaluate the Activity of Momelotinib (MMB) Versus Danazol (DAN) in Symptomatic, Anemic Subjects With Primary Myelofibrosis (PMF), Post-polycythemia Vera (PV) Myelofibrosis, or Post-essential Thrombocythemia (ET) Myelofibrosis Who Were Previously Treated With JAK Inhibitor Therapy
Study identification
- NCT ID
- NCT04173494
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Sierra Oncology LLC - a GSK company
- Industry
- Enrollment
- 195 participants
Conditions and interventions
Conditions
Interventions
- Danazol Drug
- Momelotinib Drug
- Placebo to match danazol Drug
- Placebo to match momelotinib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 6, 2020
- Primary completion
- Dec 2, 2021
- Completion
- Dec 28, 2022
- Last update posted
- Oct 31, 2023
2020 – 2022
United States locations
- U.S. sites
- 17
- U.S. states
- 12
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Hospital - Phoenix | Phoenix | Arizona | 85054 | — |
| Irvine Center for Clinical Research | Irvine | California | 92614 | — |
| Norris Comprehensive Cancer Center | Los Angeles | California | 91011 | — |
| American Institute of Research - Whittier | Whittier | California | 90603 | — |
| University of Colorado Hospital Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20057 | — |
| Moffitt Cancer Center | Tampa | Florida | 33612 | — |
| Northwest Oncology & Hematology - Rolling Meadows | Rolling Meadows | Illinois | 60008 | — |
| Washington University School of Medicine in Saint Louis | St Louis | Missouri | 63110 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Columbia University Irving Medical Center - Presbyterian Hospital | New York | New York | 10032 | — |
| Cleveland Clinic - Richard E. Jacobs Health Center | Avon | Ohio | 44011 | — |
| Gabrail Cancer Center | Canton | Ohio | 44718 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Allegheny Health Network | Pittsburgh | Pennsylvania | 15224 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| The University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 150 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04173494, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 31, 2023 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04173494 live on ClinicalTrials.gov.