Extension Study to Assess Effects of Non-interrupted Versus Interrupted and Long Term Treatment of Two Dose Regimes of Secukinumab in Subjects With Hidradenitis Suppurativa
Public ClinicalTrials.gov record NCT04179175. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double-blind, Randomized Withdrawal Extension Study of Subcutaneous Secukinumab to Demonstrate Long-term Efficacy, Safety and Tolerability in Subjects With Moderate to Severe Hidradenitis Suppurativa
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this extension study is to evaluate maintenance of Hidradenitis Suppurativa Clinical Response (HiSCR response) in either continuous or interrupted therapy (using a randomized withdrawal period) of two dose regimens and to assess long-term efficacy, safety and tolerability of Secukinumab in subjects with moderate to severe hidradenitis suppurativa completing either of the 2 Phase III studies. This is an expanded access trial for the core trials CAIN457M2301 (NCT03713619) and CAIN457M2302 (NCT03713619).
Study identification
- NCT ID
- NCT04179175
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 702 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 18, 2020 (Actual)
- Primary completion
- May 26, 2023 (Actual)
- Completion
- Jul 15, 2026 (Actual)
- Last update posted
- Aug 21, 2026
2020 – 2026
United States locations
- U.S. sites
- 29
- U.S. states
- 17
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Northwest Arkansas Center | Rogers | Arkansas | 72758 | — |
| MedDerm Associates | San Diego | California | 92103 | — |
| University Clinical Trials | San Diego | California | 92123 | — |
| Southern California Skin and Laser | Whittier | California | 92677 | — |
| Florida Academic Centers Research and Education LLC | Coral Gables | Florida | 33134 | — |
| University of MiamiHealth System | Miami | Florida | 33125 | — |
| Olympian Clinical Research | Tampa | Florida | 33609 | — |
| University Of South Florida | Tampa | Florida | 33612 | — |
| Advanced Medical Research | Sandy Springs | Georgia | 30328 | — |
| Endeavor Health | Glenview | Illinois | 60077 | — |
| Dundee Dermatology | West Dundee | Illinois | 60118 | — |
| Dawes Fretzin Clinical Rea Group | Indianapolis | Indiana | 46256 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Beth Israel Deaconess Med Center | Boston | Massachusetts | 02215 | — |
| Minnesota Clinical Study Center | New Brighton | Minnesota | 55112 | — |
| MediSearch Clinical Trials | Saint Joseph | Missouri | 64506 | — |
| St Louis U Clinical Trials | St Louis | Missouri | 63104 | — |
| WA Uni School Of Med | St Louis | Missouri | 63110 | — |
| Skin Specialists PC | Omaha | Nebraska | 68144 | — |
| Icahn School Of Med At Mount Sinai | New York | New York | 10029 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27516 | — |
| Wright State University | Fairborn | Ohio | 45324 | — |
| UP Medical Center H System | Pittsburgh | Pennsylvania | 15213-3403 | — |
| Clinical Research Ctr of Carolinas | Charleston | South Carolina | 29407 | — |
| Bellaire Dermatology Associates | Bellaire | Texas | 77401 | — |
| MDRI Baylor University | Dallas | Texas | 75246-1613 | — |
| Austin Inst for Clinical Research | Pflugerville | Texas | 78660 | — |
| Dr. Stephen Miller, MDPA | San Antonio | Texas | 78229 | — |
| Virginia Clinical Research | Norfolk | Virginia | 23507 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 162 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04179175, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 21, 2026 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04179175 live on ClinicalTrials.gov.