Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT04186871. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Placebo-Controlled, Double-Blind, Multicenter Study to Assess the Efficacy and Safety of Branebrutinib Treatment in Subjects With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Subjects With Active Rheumatoid Arthritis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and effectiveness of treatment with branebrutinib treatment in participants with active systemic Lupus Erythematosus (SLE) or Primary Sjögren's Syndrome (pSS), or branebrutinib treatment followed by open-label abatacept treatment in study participants with active Rheumatoid Arthritis (RA).
Study identification
- NCT ID
- NCT04186871
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 119 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 7, 2020 (Actual)
- Primary completion
- Dec 5, 2022 (Actual)
- Completion
- Dec 5, 2022 (Actual)
- Last update posted
- Jan 16, 2024
2020 – 2022
United States locations
- U.S. sites
- 40
- U.S. states
- 20
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0019 | Phoenix | Arizona | 85032 | — |
| Local Institution - 0002 | Covina | California | 91723 | — |
| Local Institution - 0024 | Encino | California | 91436 | — |
| Local Institution - 0034 | San Diego | California | 92108 | — |
| Local Institution - 0032 | Upland | California | 91786 | — |
| Local Institution | Brandon | Florida | 33511 | — |
| Local Institution - 0062 | DeBary | Florida | 32713 | — |
| Local Institution - 0035 | Hialeah | Florida | 33016 | — |
| Local Institution | Jacksonville | Florida | 32209 | — |
| Local Institution - 0029 | Plantation | Florida | 33324 | — |
| Local Institution - 0009 | Lawrenceville | Georgia | 30046 | — |
| Local Institution - 0014 | Skokie | Illinois | 60076 | — |
| Local Institution | Evansville | Indiana | 47715 | — |
| Local Institution - 0005 | Monroe | Louisiana | 71203 | — |
| Local Institution - 0041 | Ann Arbor | Michigan | 48109 | — |
| Local Institution - 0082 | Grand Blanc | Michigan | 48439 | — |
| Local Institution - 0096 | St Louis | Missouri | 63131 | — |
| Local Institution - 0040 | St Louis | Missouri | 63141 | — |
| Local Institution - 0056 | Lincoln | Nebraska | 68516 | — |
| Local Institution - 0007 | Las Vegas | Nevada | 89119 | — |
| Local Institution | Manhasset | New York | 11030 | — |
| Local Institution | New York | New York | 10016 | — |
| Local Institution - 0008 | Charlotte | North Carolina | 28204 | — |
| Local Institution - 0006 | Salisbury | North Carolina | 28144 | — |
| Local Institution | Minot | North Dakota | 58701 | — |
| Local Institution - 0023 | Oklahoma City | Oklahoma | 73103-2433 | — |
| Local Institution - 0022 | Oklahoma City | Oklahoma | 79112 | — |
| Local Institution - 0010 | Duncansville | Pennsylvania | 16635 | — |
| Local Institution - 0045 | Orangeburg | South Carolina | 29118 | — |
| Local Institution - 0021 | Summerville | South Carolina | 29486 | — |
| Local Institution - 0079 | Jackson | Tennessee | 38305 | — |
| Local Institution - 0001 | Memphis | Tennessee | 38119 | — |
| Local Institution - 0092 | Colleyville | Texas | 76034 | — |
| Local Institution | Dallas | Texas | 75231 | — |
| Local Institution - 0063 | Houston | Texas | 77084 | — |
| Local Institution - 0016 | Mesquite | Texas | 75150 | — |
| Local Institution - 0030 | Plano | Texas | 75024 | — |
| Local Institution - 0031 | San Antonio | Texas | 78215 | — |
| Local Institution | Waco | Texas | 76710 | — |
| Local Institution - 0083 | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 41 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04186871, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 16, 2024 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04186871 live on ClinicalTrials.gov.