LITT and Pembrolizumab in Recurrent Brain Metastasis
Public ClinicalTrials.gov record NCT04187872. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Recurrent Brain Metastasis Immune Effects and RespOnse to Laser Interstitial ThermotHerapy (LITT) and Pembrolizumab in Combination (TORCH)
Study identification
- NCT ID
- NCT04187872
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- University of Florida
- Other
- Enrollment
- 10 participants
Conditions and interventions
Conditions
- Brain Metastases, Adult
- Cervical Cancer
- Classical Hodgkin Lymphoma
- Esophageal Cancer
- Gastric Cancer
- Head and Neck Squamous Cell Cancer
- Hepatocellular Carcinoma
- Melanoma
- Merkel Cell Carcinoma
- Microsatellite Instability-High Cancer
- Non-small Cell Lung Carcinoma (NSCLC)
- Primary Mediastinal Large B-Cell Lymphoma
- Renal Cell Carcinoma (RCC)
- Small-cell Lung Cancer
- Urothelial Carcinoma
Interventions
- LITT + Pembrolizumab Combination Product
Combination Product
Eligibility (public fields only)
- Age range
- 18 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 9, 2020
- Primary completion
- Nov 30, 2023
- Completion
- Nov 30, 2023
- Last update posted
- Dec 26, 2023
2020 – 2023
United States locations
- U.S. sites
- 2
- U.S. states
- 1
- U.S. cities
- 2
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| McKnight Brain Institute of the University of Florida | Gainesville | Florida | 32611 | — |
| University of Florida Health | Jacksonville | Florida | 32209 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04187872, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 26, 2023 · Synced May 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04187872 live on ClinicalTrials.gov.